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. 1992 Mar;60(3):1229–1231. doi: 10.1128/iai.60.3.1229-1231.1992

Gamma interferon and interleukin 2, but not interleukin 4, are detectable in gamma/delta T-cell cultures after activation with bacteria.

G A Follows 1, M E Munk 1, A J Gatrill 1, P Conradt 1, S H Kaufmann 1
PMCID: PMC257618  PMID: 1531813

Abstract

Mycobacterium tuberculosis- or group A streptococcus-activated gamma/delta T cells from normal healthy individuals were negatively sorted and restimulated in vitro from 48 h. Significant amounts of gamma interferon were detected after restimulation with M. tuberculosis, group A streptococci, or Listeria monocytogenes. In contrast, interleukin 4 was undetectable in the culture supernatants. Our findings provide indirect evidence for the involvement of gamma/delta T cells in immunity against tubercle bacilli and probably other bacteria.

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Selected References

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