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. 1992 Feb;60(2):706–711. doi: 10.1128/iai.60.2.706-711.1992

Modified lymphocyte response to mitogens induced by the lipopeptide fragment derived from Mycobacterium avium serovar-specific glycopeptidolipids.

S K Tassell 1, M Pourshafie 1, E L Wright 1, M G Richmond 1, W W Barrow 1
PMCID: PMC257690  PMID: 1730507

Abstract

The beta-elimination procedure was used to obtain two major fragments of Mycobacterium avium glycopeptidolipid antigens. The lipopeptide fragment, not the oligosaccharide, diminished the mitogen-induced blastogenic response of spleen cells at concentrations lower than those which affected viability. Electron microscopy revealed an internalization of lipopeptide and disruption of intracellular organization.

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Selected References

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