Table 3.

Ethanol preference testing before and after initiation of ethanol self-administration

	Before initiation			After initiation
	Day 3	Day 4	Day 5	Day 3	Day 4	Day 5
Ethanol (ml)a	2.2 ± 0.4	2.3 ± 0.4	2.4 ± 0.4	7.0 ± 0.9	5.9 ± 0.9	7.2 ± 1.4
Water (ml) b	37.0 ± 1.5	35.8 ± 1.7	36.2 ± 1.7	35.1 ± 2.0	33.8 ± 2.2	29.8 ± 2.1
Preference c	0.05 ± 0.01	0.06 ± 0.01	0.06 ± 0.01	0.17 ± 0.02	0.15 ± 0.03	0.19 ± 0.03
Dose (g/kg/d)	0.50 ± 0.09	0.53 ± 0.09	0.53 ± 0.08	1.15 ± 0.16	0.98 ± 0.17	1.20 ± 0.26

Values shown are mean ± SEM (n=8) for ethanol and water consumption and preference.

^aaverage loss for control ethanol bottle was 2.1 ± 0.4 ml before initiation and 1.5 ± 0.1 ml after initiation

^baverage loss for control water bottle was 1.6 ± 0.3 ml before initiation and 1.5 ± 0.1 ml after initiation

^cEthanol preference was significantly higher after initiation compared with that before initiation (paired t-test, p < 0.05)