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Emergency Medicine Journal : EMJ logoLink to Emergency Medicine Journal : EMJ
letter
. 2006 Apr;23(4):325. doi: 10.1136/emj.2005.032110

Simpler thrombolysis decisions in patients with left bundle branch block

J R Benger 1
PMCID: PMC2579519  PMID: 16549591

I read the article by Reuben and Mann1 with considerable interest. This is a useful way of presenting the Sgarbossa criteria, which have high specificity for acute myocardial infarction (AMI). Unfortunately, these criteria are far too insensitive to exclude MI, being present in only 20% of patients with left bundle branch block (LBBB) and confirmed AMI.2,3 It is therefore important that less experienced practitioners do not assume that thrombolysis should be withheld if these electrocardiographic (ECG) features are absent.

In fact the simplest thrombolysis decision is that all patients with a history strongly suggestive of AMI and LBBB should receive thrombolysis, unless significant contraindications exist. Even the well rehearsed medical myths relating to the age of the LBBB are of minimal relevance, as described in an elegant editorial cited by the authors.4 Patients with LBBB have the most to gain from thrombolysis,5 but they are still failing to receive this highly effective therapy in too many cases.

In summary, therefore, where Sgarbossa criteria are seen on the ECG, AMI is highly likely. However, even in the absence of these features patients with a convincing history of AMI and LBBB should still receive thrombolysis, unless there are compelling reasons not to.

Footnotes

Competing interests: none declared

References

  • 1.Reuben A D, Mann C J. Simplifying thrombolysis decisions in patients with left bundle branch block. Emerg Med J 200522617–620. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Kontos M C, McQueen R H, Jesse R L.et al Can myocardial infarction be rapidly identified in emergency department patients who have left bundle branch block? Ann Emerg Med 200137431–438. [DOI] [PubMed] [Google Scholar]
  • 3.Li S F, Walden P L, Marcilla O.et al Electrocardiographic diagnosis of myocardial infarction in patients with left bundle branch block. Ann Emerg Med 200036561–565. [DOI] [PubMed] [Google Scholar]
  • 4.Gallagher E J. Which patients with suspected myocardial ischemia and left bundle branch block should receive thrombolytic agents? Ann Emerg Med 200137439–444. [DOI] [PubMed] [Google Scholar]
  • 5.Newby K H, Pisano E, Krikoff M W.et al Incidence and clinical relevance of the occurrence of bundle‐branch block in patients treated with thrombolytic therapy. Circulation 1999942424–2428. [DOI] [PubMed] [Google Scholar]

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