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. 1992 Nov;60(11):4973–4975. doi: 10.1128/iai.60.11.4973-4975.1992

Human neutrophil azurocidin synergizes with leukocyte elastase and cathepsin G in the killing of Capnocytophaga sputigena.

K T Miyasaki 1, A L Bodeau 1
PMCID: PMC258259  PMID: 1399008

Abstract

Azurocidin was purified in the presence of phenylmethylsulfonyl fluoride. Electrophoresis revealed at least seven species which exhibited N-terminal sequences consistent with azurocidin. Azurocidin exhibited no bactericidal activity against Capnocytophaga sputigena or other oral bacteria but synergized the bactericidal activity of enzymatically active elastase. Azurocidin also interacted synergistically with cathepsin G.

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Selected References

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