Abstract
In this article we discuss important discoveries in relation to the anatomy and physiology of the ear from Renaissance to present. Before the Renaissance, there was a paucity of knowledge of the anatomy of the ear, because of the relative inaccessibility of the temporal bone and the general perception that human dissections should not be conducted. It was not until the sixteenth century that the middle ear was described with detail. Further progress would be made between the sixteenth and eighteenth century in describing the inner ear. In the nineteenth century, technological advancement permitted a description of the cells and structures that constitute the cochlea. Von Helmholtz made further progress in hearing physiology when he postulated his resonance theory and later von Békésy when he observed a traveling wave in human cadavers within the cochlea. Brownell later made a major advance when he discovered that the ear has a mechanism for sound amplification, via outer hair cell electromotility.
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Selected References
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- Brownell W. E., Bader C. R., Bertrand D., de Ribaupierre Y. Evoked mechanical responses of isolated cochlear outer hair cells. Science. 1985 Jan 11;227(4683):194–196. doi: 10.1126/science.3966153. [DOI] [PubMed] [Google Scholar]
- Brownell W. E. Microscopic observation of cochlear hair cell motility. Scan Electron Microsc. 1984;(Pt 3):1401–1406. [PubMed] [Google Scholar]
- Brownell W. E., Spector A. A., Raphael R. M., Popel A. S. Micro- and nanomechanics of the cochlear outer hair cell. Annu Rev Biomed Eng. 2001;3:169–194. doi: 10.1146/annurev.bioeng.3.1.169. [DOI] [PubMed] [Google Scholar]
- Flock A., Cheung H. C. Actin filaments in sensory hairs of inner ear receptor cells. J Cell Biol. 1977 Nov;75(2 Pt 1):339–343. doi: 10.1083/jcb.75.2.339. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kemp D. T. Stimulated acoustic emissions from within the human auditory system. J Acoust Soc Am. 1978 Nov;64(5):1386–1391. doi: 10.1121/1.382104. [DOI] [PubMed] [Google Scholar]