Table 3.
COMT Val158Met in substance use disorders
| Author | Year | Ethnicity | Substance use disorder | Sample size | Val 158 frequency | Met 158 frequency | p value allele freq |
|---|---|---|---|---|---|---|---|
| Vandenbergh et al | 1997 | Caucasian | Polysubstance abuse (lifetime use) |
Cases = 185 Controls = 124 |
|||
| Vandenbergh et al | 2000 | ||||||
| Kauhanen et al | 2000 | ||||||
| Li et al | 2004 | Han Chinese |
Methamphetamine | Cases = 416 Controls = 435 |
0.74 0.68 |
0.26 0.32 |
0.02 |
| Beuten et al | 2005 | ||||||
| Enoch et al | 2006 | ||||||
| Horowitz et al | 2000 | ||||||
| Hosak et al | 2006 | ||||||
| Samochowiec et al | 2006 | ||||||
| Sery et al | 2006 | ||||||
| Tiihonen et al | 1999 | ||||||
| Wang et al | 2001 | ||||||
| Cevoli et al | 2006 | ||||||
| Guo et al | 2007 | ||||||
| Kweon et al | 2005 | ||||||
| Hallikainen et al | 2000 | ||||||