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. 1990 Feb;58(2):569–572. doi: 10.1128/iai.58.2.569-572.1990

Variation in expression of class 1 and class 5 outer membrane proteins during nasopharyngeal carriage of Neisseria meningitidis.

J P Woods 1, J G Cannon 1
PMCID: PMC258496  PMID: 2105277

Abstract

Accidental nasopharyngeal colonization of a laboratory worker by a human disease isolate of Neisseria meningitidis allowed us to examine the variation in expression of outer membrane components and the host humoral response over time. There were quantitative differences in class 1 outer membrane protein expression in nasopharyngeal isolates obtained at different times. Isolates also showed phase variation of all four class 5 outer membrane proteins produced by the colonizing strain. After colonization, we detected new host serum immunoglobulin G antibodies directed against class 1, class 5, and H.8 outer membrane proteins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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