Table 1.

Parameter values used to generate baseline parameter set with circadian oscillation of 24 hrs

VSP	Accumulation rate of Mp in the cytosol	1 nM h−1
VMP	Maximum enzymatic degradation rate of Mp	0.7 nM h−1
kSP	Maximum rate of P0 synthesis	0.9 h−1
VDP	Maximum enzymatic degradation rate of P2	2 nM h−1
k1	Maximum transport rate of P2 in the nucleus	0.155 h−1
k2	Maximum transport rate of PN in the cytosol	0.2 h−1
kIP	Threshold constant for transcription repression	1 nM
n	Degree of cooperativity for Hill equation	2
k11P, k12P,	Michaelis constants for kinases	2 nM
kP	Michaelis constants for phosphatases	2 nM
V1P, V3P	Maximum rates for kinases	8 nM h−1
V2P, V4P	Maximum rates for phosphatases	1 nM h−1
kDN	Decay rate of PN	0.01 h−1
α	Proportion of isoforms	0