Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1990 Jun;58(6):2021–2023. doi: 10.1128/iai.58.6.2021-2023.1990

Variation in virulence among oculogenital serovars of Chlamydia trachomatis in experimental genital tract infection.

J I Ito Jr 1, J M Lyons 1, L P Airo-Brown 1
PMCID: PMC258764  PMID: 2341189

Abstract

Seven different oculogenital serovars (D, E, F, G, H, I, and K) of Chlamydia trachomatis were inoculated intravaginally into CF-1 mice, and subsequent infection was monitored. The duration of infection was longest with serovars D and E. This may help to explain clinical surveys which demonstrate a high (50%) prevalence of these serovars. Furthermore, a comparison of the invasiveness of strains D and H demonstrated a much higher frequency of uterine horn infection with serovar D.

Full text

PDF
2021

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barnes R. C., Rompalo A. M., Stamm W. E. Comparison of Chlamydia trachomatis serovars causing rectal and cervical infections. J Infect Dis. 1987 Dec;156(6):953–958. doi: 10.1093/infdis/156.6.953. [DOI] [PubMed] [Google Scholar]
  2. Batteiger B. E., Lennington W., Newhall W. J., Katz B. P., Morrison H. T., Jones R. B. Correlation of infecting serovar and local inflammation in genital chlamydial infections. J Infect Dis. 1989 Aug;160(2):332–336. doi: 10.1093/infdis/160.2.332. [DOI] [PubMed] [Google Scholar]
  3. Brunham R. C., Kuo C., Chen W. J. Systemic Chlamydia trachomatis infection in mice: a comparison of lymphogranuloma venereum and trachoma biovars. Infect Immun. 1985 Apr;48(1):78–82. doi: 10.1128/iai.48.1.78-82.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Ito J. I., Jr, Harrison H. R., Alexander E. R., Billings L. J. Establishment of genital tract infection in the CF-1 mouse by intravaginal inoculation of a human oculogenital isolate of Chlamydia trachomatis. J Infect Dis. 1984 Oct;150(4):577–582. doi: 10.1093/infdis/150.4.577. [DOI] [PubMed] [Google Scholar]
  5. Kuo C. C., Wang S. P., Holmes K. K., Grayston J. T. Immunotypes of Chlamydia trachomatis isolates in Seattle, Washington. Infect Immun. 1983 Aug;41(2):865–868. doi: 10.1128/iai.41.2.865-868.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Mabey D. C., Forsey T., Treharne J. D. Serotypes of Chlamydia trachomatis in The Gambia. Lancet. 1987 Aug 22;2(8556):452–452. doi: 10.1016/s0140-6736(87)90984-6. [DOI] [PubMed] [Google Scholar]
  7. Tuffrey M., Falder P., Gale J., Taylor-Robinson D. Salpingitis in mice induced by human strains of Chlamydia trachomatis. Br J Exp Pathol. 1986 Aug;67(4):605–616. [PMC free article] [PubMed] [Google Scholar]
  8. Wagenvoort J. H., Suchland R. J., Stamm W. E. Serovar distribution of urogenital Chlamydia trachomatis strains in The Netherlands. Genitourin Med. 1988 Jun;64(3):159–161. doi: 10.1136/sti.64.3.159. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES