Abstract
Helicobacter pylori has been recognized as a major cause of most of the diseases of the stomach. These diseases are preceded by lesions of gastritis induced by H. pylori. This long-standing infection gives us a very good model of interaction between a bacterium and its host. We will review the direct and indirect effects of H. pylori.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Courillon-Mallet A., Launay J. M., Roucayrol A. M., Callebert J., Emond J. P., Tabuteau F., Cattan D. Helicobacter pylori infection: physiopathologic implication of N alpha-methyl histamine. Gastroenterology. 1995 Apr;108(4):959–966. doi: 10.1016/0016-5085(95)90190-6. [DOI] [PubMed] [Google Scholar]
- Covacci A., Censini S., Bugnoli M., Petracca R., Burroni D., Macchia G., Massone A., Papini E., Xiang Z., Figura N. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5791–5795. doi: 10.1073/pnas.90.12.5791. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cover T. L., Blaser M. J. Purification and characterization of the vacuolating toxin from Helicobacter pylori. J Biol Chem. 1992 May 25;267(15):10570–10575. [PubMed] [Google Scholar]
- Crabtree J. E., Taylor J. D., Wyatt J. I., Heatley R. V., Shallcross T. M., Tompkins D. S., Rathbone B. J. Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology. Lancet. 1991 Aug 10;338(8763):332–335. doi: 10.1016/0140-6736(91)90477-7. [DOI] [PubMed] [Google Scholar]
- Figura N., Guglielmetti P., Rossolini A., Barberi A., Cusi G., Musmanno R. A., Russi M., Quaranta S. Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only. J Clin Microbiol. 1989 Jan;27(1):225–226. doi: 10.1128/jcm.27.1.225-226.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ghiara P., Marchetti M., Blaser M. J., Tummuru M. K., Cover T. L., Segal E. D., Tompkins L. S., Rappuoli R. Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease. Infect Immun. 1995 Oct;63(10):4154–4160. doi: 10.1128/iai.63.10.4154-4160.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Herrington C. S. Human papillomaviruses and cervical neoplasia. II. Interaction of HPV with other factors. J Clin Pathol. 1995 Jan;48(1):1–6. doi: 10.1136/jcp.48.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Leunk R. D., Johnson P. T., David B. C., Kraft W. G., Morgan D. R. Cytotoxic activity in broth-culture filtrates of Campylobacter pylori. J Med Microbiol. 1988 Jun;26(2):93–99. doi: 10.1099/00222615-26-2-93. [DOI] [PubMed] [Google Scholar]
- Mégraud F., Neman-Simha V., Brügmann D. Further evidence of the toxic effect of ammonia produced by Helicobacter pylori urease on human epithelial cells. Infect Immun. 1992 May;60(5):1858–1863. doi: 10.1128/iai.60.5.1858-1863.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mégraud F. Toxic factors of Helicobacter pylori. Eur J Gastroenterol Hepatol. 1994 Dec;6 (Suppl 1):S5–10. [PubMed] [Google Scholar]
- Segal E. D., Falkow S., Tompkins L. S. Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylation of host cell proteins. Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1259–1264. doi: 10.1073/pnas.93.3.1259. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sherburne R., Taylor D. E. Helicobacter pylori expresses a complex surface carbohydrate, Lewis X. Infect Immun. 1995 Dec;63(12):4564–4568. doi: 10.1128/iai.63.12.4564-4568.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]