Abstract
The epidemic of pellagra in the first half of this century at its peak produced at least 250,000 cases and caused 7,000 deaths a year for several decades in 15 southern states. It also filled hospital wards in other states, which had a similar incidence but refused to report their cases. Political influences interfered, not only with surveillance of the disease, but also in its study, recognition of its cause, and the institution of preventive measures when they became known. Politicians and the general public felt that it was more acceptable for pellagra to be infectious than for it to be a form of malnutrition, a result of poverty and thus an embarrassing social problem. Retrospectively, a change in the method of milling cornmeal, degermination, which began shortly after 1900, probably accounted for the appearance of the epidemic; such a process was suggested at the time, but the suggestion was ignored.
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Selected References
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- Carpenter K. J. Effects of different methods of processing maize on its pellagragenic activity. Fed Proc. 1981 Apr;40(5):1531–1535. [PubMed] [Google Scholar]
- Funk C. Studies on pellagra: I. The influence of the milling of maize on the chemical composition and the nutritive value of maize-meal. J Physiol. 1913 Dec 19;47(4-5):389–392. doi: 10.1113/jphysiol.1913.sp001631. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Public Health Weekly Reports for FEBRUARY 19, 1926. Public Health Rep. 1926 Feb 19;41(8):297–367. [PMC free article] [PubMed] [Google Scholar]
- Public Health Weekly Reports for JUNE 26, 1914. Public Health Rep. 1914 Jun 26;29(26):1683–1752. [PMC free article] [PubMed] [Google Scholar]
- Public Health Weekly Reports for NOVEMBER 12, 1920. Public Health Rep. 1920 Nov 12;35(46):2673–2761. [PMC free article] [PubMed] [Google Scholar]
- Public Health Weekly Reports for NOVEMBER 17, 1916. Public Health Rep. 1916 Nov 17;31(46):3159–3227. [PMC free article] [PubMed] [Google Scholar]
- Public Health Weekly Reports for OCTOBER 12, 1923. Public Health Rep. 1923 Oct 12;38(41):2361–2410. [PMC free article] [PubMed] [Google Scholar]
- Public Health Weekly Reports for OCTOBER 22, 1915. Public Health Rep. 1915 Oct 22;30(43):3117–3199. [PMC free article] [PubMed] [Google Scholar]
- SYDENSTRICKER V. P. The history of pellagra, its recognition as a disorder of nutrition and its conquest. Am J Clin Nutr. 1958 Jul-Aug;6(4):409–414. doi: 10.1093/ajcn/6.4.409. [DOI] [PubMed] [Google Scholar]