Abstract
Admission of a patient to an intensive care unit for management of direct consequences of a hematologic or oncologic disease is occasionally necessary. Such problems included exchange transfusion, sepsis, compression of vital structures by malignant tumor, metabolic derangements, leukostasis, post-operative care, major sickling episodes in vital organs, and disseminated coagulopathy. More often, however, hematologic complications arise in the child critically ill from other causes, such as trauma or infections. The first two sections of this review address blood transfusion and hemostasis, topics likely to have wide application in the care of critically ill children. The last portion discusses problems unique to patients with sickling or malignant disease.
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- Abildgaard C. F., Penner J. A., Watson-Williams E. J. Anti-inhibitor Coagulant Complex (Autoplex) for treatment of factor VIII inhibitors in hemophilia. Blood. 1980 Dec;56(6):978–984. [PubMed] [Google Scholar]
- Ahn Y. S., Harrington W. J., Simon S. R., Mylvaganam R., Pall L. M., So A. G. Danazol for the treatment of idiopathic thrombocytopenic purpura. N Engl J Med. 1983 Jun 9;308(23):1396–1399. doi: 10.1056/NEJM198306093082306. [DOI] [PubMed] [Google Scholar]
- Alexander J., Dainiak N., Berger H. J., Goldman L., Johnstone D., Reduto L., Duffy T., Schwartz P., Gottschalk A., Zaret B. L. Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography. N Engl J Med. 1979 Feb 8;300(6):278–283. doi: 10.1056/NEJM197902083000603. [DOI] [PubMed] [Google Scholar]
- Allen D. M. Heparin therapy of purpura fulminans. Pediatrics. 1966 Aug;38(2):211–214. [PubMed] [Google Scholar]
- Allen J. C. The effects of cancer therapy on the nervous system. J Pediatr. 1978 Dec;93(6):903–909. doi: 10.1016/s0022-3476(78)81209-8. [DOI] [PubMed] [Google Scholar]
- Altman R., Boullon F., Rouvier J., Raca R., de la Fuente L., Favaloro R. Aspirin and prophylaxis of thromboembolic complications in patients with substitute heart valves. J Thorac Cardiovasc Surg. 1976 Jul;72(1):127–129. [PubMed] [Google Scholar]
- Ambrus C. M., Ambrus J. L., Choi T. S., Jung O., Mirand E. A., Bartfay-Szabo A. The fibrinolysin system and its relationship to disease in the newborn. Am J Pediatr Hematol Oncol. 1979 Fall;1(3):251–260. doi: 10.1097/00043426-197923000-00009. [DOI] [PubMed] [Google Scholar]
- Anderson C. B., Philpott G. W., Ferguson T. B. The treatment of malignant pleural effusions. Cancer. 1974 Apr;33(4):916–922. doi: 10.1002/1097-0142(197404)33:4<916::aid-cncr2820330405>3.0.co;2-u. [DOI] [PubMed] [Google Scholar]
- Andrew M., Bhogal M., Karpatkin M. Factors XI and XII and prekallikrein in sick and healthy premature infants. N Engl J Med. 1981 Nov 5;305(19):1130–1133. doi: 10.1056/NEJM198111053051906. [DOI] [PubMed] [Google Scholar]
- BROWNE R. A. ANAESTHESIA IN PATIENTS WITH SICKLE-CELL ANAEMIA. Br J Anaesth. 1965 Mar;37:181–188. doi: 10.1093/bja/37.3.181. [DOI] [PubMed] [Google Scholar]
- Babcock R. B., Dumper C. W., Scharfman W. B. Heparin-induced immune thrombocytopenia. N Engl J Med. 1976 Jul 29;295(5):237–241. doi: 10.1056/NEJM197607292950501. [DOI] [PubMed] [Google Scholar]
- Bachmann F., McKenna R., Cole E. R., Najafi H. The hemostatic mechanism after open-heart surgery. I. Studies on plasma coagulation factors and fibrinolysis in 512 patients after extracorporeal circulation. J Thorac Cardiovasc Surg. 1975 Jul;70(1):76–85. [PubMed] [Google Scholar]
- Barna P. Vincristine poisoning. Pediatrics. 1980 Jul;66(1):150–150. [PubMed] [Google Scholar]
- Barnard D. R., Hathaway W. E. Neonatal thrombosis. Am J Pediatr Hematol Oncol. 1979 Fall;1(3):235–244. doi: 10.1097/00043426-197923000-00007. [DOI] [PubMed] [Google Scholar]
- Barrett-Connor E. Pneumonia and pulmonary infarction in sickle cell anemia. JAMA. 1973 May 14;224(7):997–1000. [PubMed] [Google Scholar]
- Barton J. C. Nonhemolytic, noninfectious transfusion reactions. Semin Hematol. 1981 Apr;18(2):95–121. [PubMed] [Google Scholar]
- Basu D., Gallus A., Hirsh J., Cade J. A prospective study of the value of monitoring heparin treatment with the activated partial thromboplastin time. N Engl J Med. 1972 Aug 17;287(7):324–327. doi: 10.1056/NEJM197208172870703. [DOI] [PubMed] [Google Scholar]
- Baugh R. F., Hougie C. The chemistry of blood coagulation. Clin Haematol. 1979 Feb;8(1):3–30. [PubMed] [Google Scholar]
- Beck E. A. Congenital abnormalities of fibrinogen. Clin Haematol. 1979 Feb;8(1):169–181. [PubMed] [Google Scholar]
- Bennett B. Coagulation pathways: interrelationships and control mechanisms. Semin Hematol. 1977 Jul;14(3):301–318. [PubMed] [Google Scholar]
- Berger H. J., Zaret B. L. Nuclear cardiology (first of two parts). N Engl J Med. 1981 Oct 1;305(14):799–807. doi: 10.1056/NEJM198110013051405. [DOI] [PubMed] [Google Scholar]
- Berman B. W., McIntosh S., Clyne L. P., Goldberg B., Lobel J., Komp D. M. Spontaneously acquired Factor IX inhibitors in childhood. Am J Pediatr Hematol Oncol. 1981 Spring;3(1):77–81. [PubMed] [Google Scholar]
- Berman B., Krieger A., Naiman J. L. A new method for calculating volumes of blood required for partial exchange transfusion. J Pediatr. 1979 Jan;94(1):86–89. doi: 10.1016/s0022-3476(79)80363-7. [DOI] [PubMed] [Google Scholar]
- Biancaniello T., Meyer R. A., Wong K. Y., Sager C., Kaplan S. Doxorubicin cardiotoxicity in children. J Pediatr. 1980 Jul;97(1):45–50. doi: 10.1016/s0022-3476(80)80128-4. [DOI] [PubMed] [Google Scholar]
- Bick R. L. Disseminated intravascular coagulation and related syndromes: etiology, pathophysiology, diagnosis, and management. Am J Hematol. 1978;5(3):265–282. doi: 10.1002/ajh.2830050311. [DOI] [PubMed] [Google Scholar]
- Biggs R. Recent advances in the management of haemophilia and christmas disease. Clin Haematol. 1979 Feb;8(1):95–114. [PubMed] [Google Scholar]
- Bjeletich J., Hickman R. O. The Hickman indwelling catheter. Am J Nurs. 1980 Jan;80(1):62–65. [PubMed] [Google Scholar]
- Björnsson S., Preisler H., Henderson E. S. A study of antibiotic therapy in fever of unknown origin in neutropenic cancer patients. Med Pediatr Oncol. 1977;3(4):379–385. doi: 10.1002/mpo.2950030409. [DOI] [PubMed] [Google Scholar]
- Bland J. H., Laver M. B., Lowenstein E. Vasodilator effect of commercial 5 per cent plasma protein fraction solutions. JAMA. 1973 Jun 25;224(13):1721–1724. [PubMed] [Google Scholar]
- Bleyer W. A., Hakami N., Shepard T. H. The development of hemostasis in the human fetus and newborn infant. J Pediatr. 1971 Nov;79(5):838–853. doi: 10.1016/s0022-3476(71)80405-5. [DOI] [PubMed] [Google Scholar]
- Bleyer W. A. Neurologic sequelae of methotrexate and ionizing radiation: a new classification. Cancer Treat Rep. 1981;65 (Suppl 1):89–98. [PubMed] [Google Scholar]
- Bloom A. L. Clotting factor concentrates for resistant haemophilia. Br J Haematol. 1978 Sep;40(1):21–27. doi: 10.1111/j.1365-2141.1978.tb03635.x. [DOI] [PubMed] [Google Scholar]
- Bloom A. L., Peake I. R. Molecular genetics of factor VIII and its disorders. Semin Hematol. 1977 Jul;14(3):319–339. [PubMed] [Google Scholar]
- Bristow M. R., Lopez M. B., Mason J. W., Billingham M. E., Winchester M. A. Efficacy and cost of cardiac monitoring in patients receiving doxorubicin. Cancer. 1982 Jul 1;50(1):32–41. doi: 10.1002/1097-0142(19820701)50:1<32::aid-cncr2820500108>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
- Brodeur G. M., O'Neill P. J., Willimas J. A. Acquired inhibitors of coagulation in nonhemophiliac children. J Pediatr. 1980 Mar;96(3 Pt 1):439–441. doi: 10.1016/s0022-3476(80)80693-7. [DOI] [PubMed] [Google Scholar]
- Brody J. I., Goldsmith M. H., Park S. K., Soltys H. D. Symptomatic crises of sickle cell anemia treated by limited exchange transfusion. Ann Intern Med. 1970 Mar;72(3):327–330. doi: 10.7326/0003-4819-72-3-327. [DOI] [PubMed] [Google Scholar]
- Broekmans A. W., Veltkamp J. J., Bertina R. M. Congenital protein C deficiency and venous thromboembolism. A study of three Dutch families. N Engl J Med. 1983 Aug 11;309(6):340–344. doi: 10.1056/NEJM198308113090604. [DOI] [PubMed] [Google Scholar]
- Brook I., Martin W. J. Aerobic and anaerobic bacteriology of perirectal abscess in children. Pediatrics. 1980 Aug;66(2):282–284. [PubMed] [Google Scholar]
- Buchanan G. R., Glader B. E. Leukocyte counts in children with sickle cell disease. Comparative values in the steady state, vaso-occlusive crisis, and bacterial infection. Am J Dis Child. 1978 Apr;132(4):396–398. doi: 10.1001/archpedi.1978.02120290068013. [DOI] [PubMed] [Google Scholar]
- Buchanan G. R. Neonatal coagulation: normal physiology and pathophysiology. Clin Haematol. 1978 Feb;7(1):85–109. [PubMed] [Google Scholar]
- Buchanan G. R., Smith S. J., Holtkamp C. A., Fuseler J. P. Bacterial infection and splenic reticuloendothelial function in children with hemoglobin SC disease. Pediatrics. 1983 Jul;72(1):93–98. [PubMed] [Google Scholar]
- Buchholz D. H. Blood transfusion: merits of component therapy. I. The clinical use of red cells, platelets, and granulocytes. J Pediatr. 1974 Jan;84(1):1–15. doi: 10.1016/s0022-3476(74)80546-9. [DOI] [PubMed] [Google Scholar]
- Buckalew V. M., Jr, Someren A. Renal manifestations of sickle cell disease. Arch Intern Med. 1974 Apr;133(4):660–669. [PubMed] [Google Scholar]
- Burch J. W., Majerus P. W. The role of prostaglandins in platelet function. Semin Hematol. 1979 Jul;16(3):196–207. [PubMed] [Google Scholar]
- Burger P. C., Mahley M. S., Jr, Dudka L., Vogel F. S. The morphologic effects of radiation administered therapeutically for intracranial gliomas: a postmortem study of 25 cases. Cancer. 1979 Oct;44(4):1256–1272. doi: 10.1002/1097-0142(197910)44:4<1256::aid-cncr2820440415>3.0.co;2-t. [DOI] [PubMed] [Google Scholar]
- Burrington J. D., Smith M. D. Elective and emergency surgery in children with sickle cell disease. Surg Clin North Am. 1976 Feb;56(1):55–71. doi: 10.1016/s0039-6109(16)40835-2. [DOI] [PubMed] [Google Scholar]
- Bussel J. B., Schulman I., Hilgartner M. W., Barandun S. Intravenous use of gammaglobulin in the treatment of chronic immune thrombocytopenic purpura as a means to defer splenectomy. J Pediatr. 1983 Oct;103(4):651–654. doi: 10.1016/s0022-3476(83)80608-8. [DOI] [PubMed] [Google Scholar]
- Carpentieri U., Haggard M. E., Lockhart L. H., Gustavson L. P., Box Q. T., West E. F. Clinical experience in prevention of candidiasis by nystatin in children with acute lymphocytic leukemia. J Pediatr. 1978 Apr;92(4):593–595. doi: 10.1016/s0022-3476(78)80298-4. [DOI] [PubMed] [Google Scholar]
- Carpentieri U., Patten E. V., Chamberlin P. A., Young A. D., Hitter M. E. Leukapheresis in a 3-year-old child with lymphoma in leukemic transformation. J Pediatr. 1979 Jun;94(6):919–921. doi: 10.1016/s0022-3476(79)80215-2. [DOI] [PubMed] [Google Scholar]
- Champion L. A., Luddy R. E., Schwartz A. D. Disseminated intravascular coagulation in childhood acute lymphocytic leukemia with poor prognostic features. Cancer. 1978 Apr;41(4):1642–1646. doi: 10.1002/1097-0142(197804)41:4<1642::aid-cncr2820410456>3.0.co;2-r. [DOI] [PubMed] [Google Scholar]
- Chernik N. L., Armstrong D., Posner J. B. Central nervous system infections in patients with cancer. Changing patterns. Cancer. 1977 Jul;40(1):268–274. doi: 10.1002/1097-0142(197707)40:1<268::aid-cncr2820400139>3.0.co;2-g. [DOI] [PubMed] [Google Scholar]
- Chessells J. M. Acute lymphoblastic leukemia. Semin Hematol. 1982 Jul;19(3):155–171. [PubMed] [Google Scholar]
- Chilcote R. R., Baehner R. L. Septicemia in association with acute lymphoblastic leukemia. J Pediatr. 1979 May;94(5):715–718. doi: 10.1016/s0022-3476(79)80136-5. [DOI] [PubMed] [Google Scholar]
- Coleman R. A., Sommerville H. M., Friedman H. S., Falletta J. M., Kinney T. R. Insulin therapy for ketolactic acidosis complicating malignancy. J Pediatr. 1982 Apr;100(4):584–587. doi: 10.1016/s0022-3476(82)80759-2. [DOI] [PubMed] [Google Scholar]
- Conrad M. E. Diseases transmissible by blood transfusion: viral hepatitis and other infectious disorders. Semin Hematol. 1981 Apr;18(2):122–146. [PubMed] [Google Scholar]
- Conte J. E., Jr, Hadley W. K., Sande M. Infection-control guidelines for patients with the acquired immunodeficiency syndrome (AIDS). N Engl J Med. 1983 Sep 22;309(12):740–744. doi: 10.1056/nejm198309223091228. [DOI] [PubMed] [Google Scholar]
- Corrigan J. J., Jr Activation of coagulation and disseminated intravascular coagulation in the newborn. Am J Pediatr Hematol Oncol. 1979 Fall;1(3):245–249. doi: 10.1097/00043426-197923000-00008. [DOI] [PubMed] [Google Scholar]
- Corrigan J. J., Jr Coagulation inhibitors. Am J Pediatr Hematol Oncol. 1980 Fall;2(3):281–288. [PubMed] [Google Scholar]
- Corrigan J. J., Jr, Earnest D. L. Factor II antigen in liver disease and warfarin-induced vitamin K deficiency: correlation with coagulant activity using Echis venom. Am J Hematol. 1980;8(3):249–255. doi: 10.1002/ajh.2830080302. [DOI] [PubMed] [Google Scholar]
- Corrigan J. J., Jr Heparin therapy in bacterial septicemia. J Pediatr. 1977 Nov;91(5):695–700. doi: 10.1016/s0022-3476(77)81017-2. [DOI] [PubMed] [Google Scholar]
- Curran J. W., Lawrence D. N., Jaffe H., Kaplan J. E., Zyla L. D., Chamberland M., Weinstein R., Lui K. J., Schonberger L. B., Spira T. J. Acquired immunodeficiency syndrome (AIDS) associated with transfusions. N Engl J Med. 1984 Jan 12;310(2):69–75. doi: 10.1056/NEJM198401123100201. [DOI] [PubMed] [Google Scholar]
- D'Angio G. J., Clatworthy H. W., Evans A. E., Newton W. A., Jr, Tefft M. Is the risk of morbidity and rare mortality worth the cure? Cancer. 1978 Jan;41(1):377–380. doi: 10.1002/1097-0142(197801)41:1<377::aid-cncr2820410151>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
- D'Angio G. J. Complications of treatment encountered in lymphoma-leukemia long-term survivors. Cancer. 1978 Aug;42(2 Suppl):1015–1025. doi: 10.1002/1097-0142(197808)42:2+<1015::aid-cncr2820420725>3.0.co;2-g. [DOI] [PubMed] [Google Scholar]
- Daly P. A., Schiffer C. A., Wiernik P. H. Acute promyelocytic leukemia--clinical management of 15 patients. Am J Hematol. 1980;8(4):347–359. doi: 10.1002/ajh.2830080403. [DOI] [PubMed] [Google Scholar]
- Desforges J. F., Warth J. The management of sickle cell disease in pregnancy. Clin Perinatol. 1974 Sep;1(2):385–394. [PubMed] [Google Scholar]
- Deykin D. Emerging concepts of platelet function. N Engl J Med. 1974 Jan 17;290(3):144–151. doi: 10.1056/NEJM197401172900308. [DOI] [PubMed] [Google Scholar]
- Didisheim P., Fuster V. Actions and clinical status of platelet-suppressive agents. Semin Hematol. 1978 Jan;15(1):55–72. [PubMed] [Google Scholar]
- Dindogru A., Barcos M., Henderson E. S., Wallace H. J., Jr Electrocardiographic changes following adriamycin treatment. Med Pediatr Oncol. 1978;5(1):65–71. doi: 10.1002/mpo.2950050110. [DOI] [PubMed] [Google Scholar]
- Drapkin R. L., Gee T. S., Dowling M. D., Arlin Z., McKenzie S., Kempin S., Clarkson B. Prophylactic heparin therapy in acute promyelocytic leukemia. Cancer. 1978 Jun;41(6):2484–2490. doi: 10.1002/1097-0142(197806)41:6<2484::aid-cncr2820410659>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
- Drapkin R. L., Gee T. S., Dowling M. D., Arlin Z., McKenzie S., Kempin S., Clarkson B. Prophylactic heparin therapy in acute promyelocytic leukemia. Cancer. 1978 Jun;41(6):2484–2490. doi: 10.1002/1097-0142(197806)41:6<2484::aid-cncr2820410659>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
- Eyre H. J., Ward J. H., Priebat D. A. Adult acute leukemia. Aggressive treatment improves survival. Cancer. 1983 Jun 15;51(12 Suppl):2460–2468. doi: 10.1002/1097-0142(19830615)51:12+<2460::aid-cncr2820511314>3.0.co;2-y. [DOI] [PubMed] [Google Scholar]
- Fehr J., Hofmann V., Kappeler U. Transient reversal of thrombocytopenia in idiopathic thrombocytopenic purpura by high-dose intravenous gamma globulin. N Engl J Med. 1982 May 27;306(21):1254–1258. doi: 10.1056/NEJM198205273062102. [DOI] [PubMed] [Google Scholar]
- Feigin R. D., Shearer W. T. Opportunistic infection in children. I. In the compromised host. J Pediatr. 1975 Oct;87(4):507–514. doi: 10.1016/s0022-3476(75)80810-9. [DOI] [PubMed] [Google Scholar]
- Feinstein D. I. Diagnosis and management of disseminated intravascular coagulation: the role of heparin therapy. Blood. 1982 Aug;60(2):284–287. [PubMed] [Google Scholar]
- Feldman S., Hughes W. T., Daniel C. B. Varicella in children with cancer: Seventy-seven cases. Pediatrics. 1975 Sep;56(3):388–397. [PubMed] [Google Scholar]
- Feldman S., Hughes W. T., Kim H. Y. Herpes zoster in children with cancer. Am J Dis Child. 1973 Aug;126(2):178–184. doi: 10.1001/archpedi.1973.02110190156009. [DOI] [PubMed] [Google Scholar]
- Foote G. A., Schabel S. I., Hodges M. Pulmonary complications of the flow-directed balloon-tipped catheter. N Engl J Med. 1974 Apr 25;290(17):927–931. doi: 10.1056/NEJM197404252901702. [DOI] [PubMed] [Google Scholar]
- Forbes C. D., Lowe G. D., Prentice C. R. Thrombolytic therapy--indications, advantages and disadvantages. Angiology. 1978 Nov;29(11):783–790. doi: 10.1177/000331977802901101. [DOI] [PubMed] [Google Scholar]
- Ford J. M., Cullen M. H., Lucey J. J., Tobias J. S., Lister T. A. Fatal graft-versus-host disease following transfusion of granulocytes from normal donors. Lancet. 1976 Nov 27;2(7996):1167–1169. doi: 10.1016/s0140-6736(76)91682-2. [DOI] [PubMed] [Google Scholar]
- Forman W. B., Bayer G. A simplified method for monitoring heparin therapy at the bedside: the activated whole blood clotting time. Am J Hematol. 1981 Nov;11(3):277–281. doi: 10.1002/ajh.2830110308. [DOI] [PubMed] [Google Scholar]
- Freeman J. E., Johnston P. G., Voke J. M. Somnolence after prophylactic cranial irradiation in children with acute lymphoblastic leukaemia. Br Med J. 1973 Dec 1;4(5891):523–525. doi: 10.1136/bmj.4.5891.523. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GREEN T. W., CONLEY C. L., BERTHRONG M. [The liver in sickle cell anemia]. Bull Johns Hopkins Hosp. 1953 Feb;92(2):99–127. [PubMed] [Google Scholar]
- Garwicz S., Aronson S., Elmqvist D., Landberg T. Postirradiation syndrome and eeg findings in children with acute lymphoblastic leukaemia. Acta Paediatr Scand. 1975 May;64(3):399–403. doi: 10.1111/j.1651-2227.1975.tb03854.x. [DOI] [PubMed] [Google Scholar]
- Genton E. Guidelines for heparin therapy. Ann Intern Med. 1974 Jan;80(1):77–82. doi: 10.7326/0003-4819-80-1-77. [DOI] [PubMed] [Google Scholar]
- George S. L., Fernbach D. J., Lee E. T. Early deaths in newly diagnosed cases of pediatric acute leukemia: a Southwest Oncology Group Study. Cancer. 1978 Aug;42(2):781–786. doi: 10.1002/1097-0142(197808)42:2<781::aid-cncr2820420250>3.0.co;2-p. [DOI] [PubMed] [Google Scholar]
- Gershon A. A., Steinberg S., Brunell P. A. Zoster immune globulin. A further assessment. N Engl J Med. 1974 Jan 31;290(5):243–245. doi: 10.1056/NEJM197401312900503. [DOI] [PubMed] [Google Scholar]
- Gilbertson A. A. Anaesthesia in West African patients with sickle-cell anaemia, haemoglobin SC disease, and sickle-cell trait. Br J Anaesth. 1965 Aug;37(8):614–622. doi: 10.1093/bja/37.8.614. [DOI] [PubMed] [Google Scholar]
- Gilchrist G. S., Fountain K. S., Dearth J. C., Smithson W. A., Burgert E. O., Jr Cranial irradiation in the management of extreme leukemic leukocytosis complicating childhood acute lymphocytic leukemia. J Pediatr. 1981 Feb;98(2):257–259. doi: 10.1016/s0022-3476(81)80653-1. [DOI] [PubMed] [Google Scholar]
- Gill F. M., Shapiro S. S., Schwartz E. Severe congenital hypoprothrombinemia. J Pediatr. 1978 Aug;93(2):264–266. doi: 10.1016/s0022-3476(78)80515-0. [DOI] [PubMed] [Google Scholar]
- Gingrich R. D., Hoak J. C. Platelet-endothelial cell interactions. Semin Hematol. 1979 Jul;16(3):208–220. [PubMed] [Google Scholar]
- Glicksman A. S., Nickson J. J. Acute and late reactions to irradiation in the treatment of Hodgkin's disease. Arch Intern Med. 1973 Mar;131(3):369–373. [PubMed] [Google Scholar]
- Goldfinger D. Acute hemolytic transfusion reactions--a fresh look at pathogenesis and considerations regarding therapy. Transfusion. 1977 Mar-Apr;17(2):85–98. doi: 10.1046/j.1537-2995.1977.17277151928.x. [DOI] [PubMed] [Google Scholar]
- Goorin A. M., Borow K. M., Goldman A., Williams R. G., Henderson I. C., Sallan S. E., Cohen H., Jaffe N. Congestive heart failure due to adriamycin cardiotoxicity: its natural history in children. Cancer. 1981 Jun 15;47(12):2810–2816. doi: 10.1002/1097-0142(19810615)47:12<2810::aid-cncr2820471210>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]
- Gralnick H. R., Marchesi S., Givelber H. Intravascular coagulation in acute leukemia: clinical and subclinical abnormalities. Blood. 1972 Nov;40(5):709–718. [PubMed] [Google Scholar]
- Graus F., Walker R. W., Allen J. C. Brain metastases in children. J Pediatr. 1983 Oct;103(4):558–561. doi: 10.1016/s0022-3476(83)80583-6. [DOI] [PubMed] [Google Scholar]
- Green D. M. Fever and bacteremia in children and adolescents with acute lymphoblastic leukemia. Am J Pediatr Hematol Oncol. 1982 Fall;4(3):263–271. [PubMed] [Google Scholar]
- Greenwalt T. J. Pathogenesis and management of hemolytic transfusion reactions. Semin Hematol. 1981 Apr;18(2):84–94. [PubMed] [Google Scholar]
- Gérard P., Moriau M., Bachy A., Malvaux P., De Meyer R. Meningococcal purpura: report of 19 patients treated with heparin. J Pediatr. 1973 May;82(5):780–786. doi: 10.1016/s0022-3476(73)80066-6. [DOI] [PubMed] [Google Scholar]
- Hall R. T., Rhodes P. G., Turner E. A., Braun W. J. Protamine sulfate titration for heparin activity in neonates with indwelling umbilical catheters. J Pediatr. 1976 Mar;88(3):467–472. doi: 10.1016/s0022-3476(76)80270-3. [DOI] [PubMed] [Google Scholar]
- Ham J. M. Hypoprothrombinaemia in patients undergoing prolonged intensive care. Med J Aust. 1971 Oct 2;2(14):716–718. doi: 10.5694/j.1326-5377.1971.tb92503.x. [DOI] [PubMed] [Google Scholar]
- Hamilton W., Rosenthal A., Berwick D., Nadas A. S. Angina pectoris in a child with sickle cell anemia. Pediatrics. 1978 Jun;61(6):911–914. [PubMed] [Google Scholar]
- Hardisty R. M. Hereditary disorders of platelet function. Clin Haematol. 1983 Feb;12(1):153–173. [PubMed] [Google Scholar]
- Harguindey S., DeCastro L., Barcos M., Getaz E. P., Henderson E. S., Freeman A. Hypercalcemia complicating childhood malignancies: a report of seven cases with some pathophysiological considerations. Cancer. 1979 Dec;44(6):2280–2290. doi: 10.1002/1097-0142(197912)44:6<2280::aid-cncr2820440642>3.0.co;2-z. [DOI] [PubMed] [Google Scholar]
- Harker L. A., Slichter S. J. The bleeding time as a screening test for evaluation of platelet function. N Engl J Med. 1972 Jul 27;287(4):155–159. doi: 10.1056/NEJM197207272870401. [DOI] [PubMed] [Google Scholar]
- Harlan J. M. Thrombocytopenia due to non-immune platelet destruction. Clin Haematol. 1983 Feb;12(1):39–68. [PubMed] [Google Scholar]
- Harpel P. C. Protease inhibitors--a precarious balance. N Engl J Med. 1983 Sep 22;309(12):725–726. doi: 10.1056/NEJM198309223091210. [DOI] [PubMed] [Google Scholar]
- Hathaway W. E. Bleeding disorders due to platelet dysfunction. Am J Dis Child. 1971 Feb;121(2):127–134. doi: 10.1001/archpedi.1971.02100130081009. [DOI] [PubMed] [Google Scholar]
- Higby D. J., Burnett D. Granulocyte transfusions: current status. Blood. 1980 Jan;55(1):2–8. [PubMed] [Google Scholar]
- Hirsch M. S., Schooley R. T. Drug therapy. Treatment of herpesvirus infections. N Engl J Med. 1983 Oct 20;309(16):963–970. doi: 10.1056/NEJM198310203091607. [DOI] [PubMed] [Google Scholar]
- Hoecker J. L., Pickering L. K., Groschel D., Kohl S., van Eys J. Current concepts of bacteremia in children with malignancies. Cancer. 1979 Nov;44(5):1939–1944. doi: 10.1002/1097-0142(197911)44:5<1939::aid-cncr2820440557>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
- Holzmann L., Finn H., Lichtman H. C., Harmel M. H. Anesthesia in patients with sickle cell disease: a review of 112 cases. Anesth Analg. 1969 Jul-Aug;48(4):566–572. [PubMed] [Google Scholar]
- Horger E. O., 3rd Sickle cell and sickle cell-hemoglobin C disease during pregnancy. Obstet Gynecol. 1972 Jun;39(6):873–879. [PubMed] [Google Scholar]
- Horowitz H. I., Stein I. M., Cohen B. D., White J. G. Further studies on the platelet-inhibitory effect of guanidinosuccinic acid and its role in uremic bleeding. Am J Med. 1970 Sep;49(3):336–345. doi: 10.1016/s0002-9343(70)80025-0. [DOI] [PubMed] [Google Scholar]
- Hougie C., Mc Pherson R. A., Brown J. E., Lakin-Thomas P. L., Melaragno A., Aronson L., Baugh R. F. The Passovoy defect: further characterization of a hereditary hemorrhagic diathesis. N Engl J Med. 1978 May 11;298(19):1045–1048. doi: 10.1056/NEJM197805112981902. [DOI] [PubMed] [Google Scholar]
- Hughes W. T., Feldman S., Chaudhary S. C., Ossi M. J., Cox F., Sanyal S. K. Comparison of pentamidine isethionate and trimethoprim-sulfamethoxazole in the treatment of Pneumocystis carinii pneumonia. J Pediatr. 1978 Feb;92(2):285–291. doi: 10.1016/s0022-3476(78)80028-6. [DOI] [PubMed] [Google Scholar]
- Hughes W. T., Feldman S., Cox F. Infectious diseases in children with cancer. Pediatr Clin North Am. 1974 Aug;21(3):583–615. doi: 10.1016/s0031-3955(16)33027-9. [DOI] [PubMed] [Google Scholar]
- Hughes W. T. Pneumocystis carinii pneumonia. N Engl J Med. 1977 Dec 22;297(25):1381–1383. doi: 10.1056/NEJM197712222972505. [DOI] [PubMed] [Google Scholar]
- Hull R., Delmore T., Genton E., Hirsh J., Gent M., Sackett D., McLoughlin D., Armstrong P. Warfarin sodium versus low-dose heparin in the long-term treatment of venous thrombosis. N Engl J Med. 1979 Oct 18;301(16):855–858. doi: 10.1056/NEJM197910183011602. [DOI] [PubMed] [Google Scholar]
- Izawa T., Ihara T., Hattori A., Iwasa T., Kamiya H., Sakurai M., Takahashi M. Application of a live varicella vaccine in children with acute leukemia or other malignant diseases. Pediatrics. 1977 Dec;60(6):805–809. [PubMed] [Google Scholar]
- Jaffe N., Paed D., Kim B. S., Vawter G. F. Hypocalcemia--a complication of childhood leukemia. Cancer. 1972 Feb;29(2):392–398. doi: 10.1002/1097-0142(197202)29:2<392::aid-cncr2820290220>3.0.co;2-a. [DOI] [PubMed] [Google Scholar]
- Jiménez R., Navarrete M., Jiménez E., Mora L. A., Robles G. Vitamin K-dependent clotting factors in normal breast-fed infants. J Pediatr. 1982 Mar;100(3):424–426. doi: 10.1016/s0022-3476(82)80450-2. [DOI] [PubMed] [Google Scholar]
- Kalter R. D., Saul C. M., Wetstein L., Soriano C., Reiss R. F. Cardiopulmonary bypass. Associated hemostatic abnormalities. J Thorac Cardiovasc Surg. 1979 Mar;77(3):427–435. [PubMed] [Google Scholar]
- Kamen B. A., Summers C. P., Pearson H. A. Exchange transfusion as a treatment for hyperleukocytosis, anemia, and metabolic abnormalities in a patient with leukemia. J Pediatr. 1980 Jun;96(6):1045–1046. doi: 10.1016/s0022-3476(80)80638-x. [DOI] [PubMed] [Google Scholar]
- Kaplan M. H., Rosen P. P., Armstrong D. Cryptococcosis in a cancer hospital: clinical and pathological correlates in forty-six patients. Cancer. 1977 May;39(5):2265–2274. doi: 10.1002/1097-0142(197705)39:5<2265::aid-cncr2820390546>3.0.co;2-x. [DOI] [PubMed] [Google Scholar]
- Kaufman I. A., Kung F. H., Koenig H. M., Giammona S. T. Overdosage with vincristine. J Pediatr. 1976 Oct;89(4):671–674. doi: 10.1016/s0022-3476(76)80416-7. [DOI] [PubMed] [Google Scholar]
- Keating M. J., Sethi M. R., Bodey G. P., Samaan N. A. Hypocalcemia with hypoparathyroidism and renal tubular dysfunction associated with aminoglycoside therapy. Cancer. 1977 Apr;39(4):1410–1414. doi: 10.1002/1097-0142(197704)39:4<1410::aid-cncr2820390409>3.0.co;2-d. [DOI] [PubMed] [Google Scholar]
- Kelton J. G. Antiplatelet agents: rationale and results. Clin Haematol. 1983 Feb;12(1):311–354. [PubMed] [Google Scholar]
- Kernoff P. B. The relevance of factor VIII inactivation characteristics in the treatment of patients with antibodies directed against factor VIII. Br J Haematol. 1972 Jun;22(6):735–742. doi: 10.1111/j.1365-2141.1972.tb05718.x. [DOI] [PubMed] [Google Scholar]
- Kirs P. J., Herman R. M. Neuromotor and neuropsychological manifestations of "total therapy" in children with acute lymphoblastic leukemia. Cancer Treat Rev. 1980 Jun;7(2):85–94. doi: 10.1016/s0305-7372(80)80018-1. [DOI] [PubMed] [Google Scholar]
- Kitchens C. S., Newcomb T. F. Factor XIII. Medicine (Baltimore) 1979 Nov;58(6):413–429. doi: 10.1097/00005792-197911000-00002. [DOI] [PubMed] [Google Scholar]
- Kluft C., Vellenga E., Brommer E. J., Wijngaards G. A familial hemorrhagic diathesis in a Dutch family: an inherited deficiency of alpha 2-antiplasmin. Blood. 1982 Jun;59(6):1169–1180. [PubMed] [Google Scholar]
- Komp D. M., Selden R. F., Jr Coagulation abnormalities in cystic fibrosis. Chest. 1970 Nov;58(5):501–503. doi: 10.1378/chest.58.5.501. [DOI] [PubMed] [Google Scholar]
- Kramer S., Lee K. F. Complications of radiation therapy: the central nervous system. Semin Roentgenol. 1974 Jan;9(1):75–83. doi: 10.1016/0037-198x(74)90011-x. [DOI] [PubMed] [Google Scholar]
- Krivit W. Adriamycin cardiotoxicity amelioration by alpha-tocopherol. Am J Pediatr Hematol Oncol. 1979 Summer;1(2):151–153. [PubMed] [Google Scholar]
- Ladisch S., Pizzo P. A. Staphylococcus aureus sepsis in children with cancer. Pediatrics. 1978 Feb;61(2):231–234. [PubMed] [Google Scholar]
- Lambert C. J., Marengo-Rowe A. J., Leveson J. E., Green R. H., Thiele J. P., Geisler G. F., Adam M., Mitchel B. F. The treatment of postperfusion bleeding using epsilon-aminocaproic acid, cryoprecipitate, fresh-frozen plasma, and protamine sulfate. Ann Thorac Surg. 1979 Nov;28(5):440–444. doi: 10.1016/s0003-4975(10)63153-0. [DOI] [PubMed] [Google Scholar]
- Landesman S. H., Rao S. P., Ahonkhai V. I. Infections in children with sickle cell anemia. Special reference to pneumococcal and salmonella infections. Am J Pediatr Hematol Oncol. 1982 Winter;4(4):407–418. doi: 10.1097/00043426-198224000-00008. [DOI] [PubMed] [Google Scholar]
- Laros R. K., Jr, Kalstone C. E. Sickle cell beta-thalassemia and pregnancy. Obstet Gynecol. 1971 Jan;37(1):67–71. [PubMed] [Google Scholar]
- Lau S. O., Tkachuck J. Y., Hasegawa D. K., Edson J. R. Plasminogen and antithrombin III deficiencies in the childhood nephrotic syndrome associated with plasminogenuria and antithrombinuria. J Pediatr. 1980 Mar;96(3 Pt 1):390–392. doi: 10.1016/s0022-3476(80)80678-0. [DOI] [PubMed] [Google Scholar]
- Lederman M. M., Ratnoff O. D., Scillian J. J., Jones P. K., Schacter B. Impaired cell-mediated immunity in patients with classic hemophilia. N Engl J Med. 1983 Jan 13;308(2):79–83. doi: 10.1056/NEJM198301133080205. [DOI] [PubMed] [Google Scholar]
- Leichtman D. A., Brewer G. J. Elevated plasma levels of fibrinopeptide A during sickle cell anemia pain crisis--evidence for intravascular coagulation. Am J Hematol. 1978;5(3):183–190. doi: 10.1002/ajh.2830050303. [DOI] [PubMed] [Google Scholar]
- Levin M., Hjelm M., Kay J. D., Pincott J. R., Gould J. D., Dinwiddie R., Matthew D. J. Haemorrhagic shock and encephalopathy: a new syndrome with a high mortality in young children. Lancet. 1983 Jul 9;2(8341):64–67. doi: 10.1016/s0140-6736(83)90057-0. [DOI] [PubMed] [Google Scholar]
- Levine A. S., Deisseroth A. B. Recent developments in the supportive therapy of acute myelogenous leukemia. Cancer. 1978 Aug;42(2 Suppl):883–894. doi: 10.1002/1097-0142(197808)42:2+<883::aid-cncr2820420710>3.0.co;2-f. [DOI] [PubMed] [Google Scholar]
- Levine D. H. Calculation of volumes for exchange transfusion. J Pediatr. 1980 Nov;97(5):870–871. doi: 10.1016/s0022-3476(80)80298-8. [DOI] [PubMed] [Google Scholar]
- Lewis A. B., Pilkington R., Takahashi M., Siegel S. E. Echocardiographic assessment of anthracycline cardiotoxicity in children. Med Pediatr Oncol. 1978;5(1):167–175. doi: 10.1002/mpo.2950050123. [DOI] [PubMed] [Google Scholar]
- Lichtman M. A., Rowe J. M. Hyperleukocytic leukemias: rheological, clinical, and therapeutic considerations. Blood. 1982 Aug;60(2):279–283. [PubMed] [Google Scholar]
- Lindsay J., Jr, Meshel J. C., Patterson R. H. The cardiovascular manifestations of sickle cell disease. Arch Intern Med. 1974 Apr;133(4):643–651. [PubMed] [Google Scholar]
- Logan L. J., Rapaport S. I., Maher I. Albinism and abnormal platelet function. N Engl J Med. 1971 Jun 17;284(24):1340–1345. doi: 10.1056/NEJM197106172842402. [DOI] [PubMed] [Google Scholar]
- Lowe G. D., Forbes C. D. Laboratory diagnosis of congenital coagulation defects. Clin Haematol. 1979 Feb;8(1):79–94. [PubMed] [Google Scholar]
- Lusher J. M., Haghighat H., Khalifa A. S. A prophylactic transfusion program for children with sickle cell anemia complicated by CNS infarction. Am J Hematol. 1976;1(2):265–273. doi: 10.1002/ajh.2830010210. [DOI] [PubMed] [Google Scholar]
- Mannucci P. M., Vigano S. Deficiencies of protein C, an inhibitor of blood coagulation. Lancet. 1982 Aug 28;2(8296):463–467. doi: 10.1016/s0140-6736(82)90494-9. [DOI] [PubMed] [Google Scholar]
- Mauer A. M., Simone J. V., Pratt C. B. Current progress in the treatment of the child with cancer. J Pediatr. 1977 Oct;91(4):523–539. doi: 10.1016/s0022-3476(77)80497-6. [DOI] [PubMed] [Google Scholar]
- McDonald M. M., Hathaway W. E. Anticoagulant therapy by continuous heparinization in newborn and older infants. J Pediatr. 1982 Sep;101(3):451–457. doi: 10.1016/s0022-3476(82)80086-3. [DOI] [PubMed] [Google Scholar]
- McIntosh S., Fischer D. B., Rothman S. G., Rosenfield N., Lobel J. S., O'Brien R. Intracranial calcifications in childhood leukemia. An association with systemic chemotherapy. J Pediatr. 1977 Dec;91(6):909–913. doi: 10.1016/s0022-3476(77)80888-3. [DOI] [PubMed] [Google Scholar]
- McIntosh S., Klatskin E. H., O'Brien R. T., Aspnes G. T., Kammerer B. L., Snead C., Kalavsky S. M., Pearson H. A. Chronic neurologic disturbance in childhood leukemia. Cancer. 1976 Feb;37(2):853–857. doi: 10.1002/1097-0142(197602)37:2<853::aid-cncr2820370234>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
- McIntosh S., Rooks Y., Ritchey A. K., Pearson H. A. Fever in young children with sickle cell disease. J Pediatr. 1980 Feb;96(2):199–204. doi: 10.1016/s0022-3476(80)80802-x. [DOI] [PubMed] [Google Scholar]
- McMillan R. Chronic idiopathic thrombocytopenic purpura. N Engl J Med. 1981 May 7;304(19):1135–1147. doi: 10.1056/NEJM198105073041904. [DOI] [PubMed] [Google Scholar]
- McMillan R. Immune thrombocytopenia. Clin Haematol. 1983 Feb;12(1):69–88. [PubMed] [Google Scholar]
- Meadows A. T., Gordon J., Massari D. J., Littman P., Fergusson J., Moss K. Declines in IQ scores and cognitive dysfunctions in children with acute lymphocytic leukaemia treated with cranial irradiation. Lancet. 1981 Nov 7;2(8254):1015–1018. doi: 10.1016/s0140-6736(81)91216-2. [DOI] [PubMed] [Google Scholar]
- Medoff G., Kobayashi G. S. Strategies in the treatment of systemic fungal infections. N Engl J Med. 1980 Jan 17;302(3):145–155. doi: 10.1056/NEJM198001173020304. [DOI] [PubMed] [Google Scholar]
- Menitove J. E., Aster R. H. Transfusion of platelets and plasma products. Clin Haematol. 1983 Feb;12(1):239–266. [PubMed] [Google Scholar]
- Merigan T. C., Rand K. H., Pollard R. B., Abdallah P. S., Jordan G. W., Fried R. P. Human leukocyte interferon for the treatment of herpes zoster in patients with cancer. N Engl J Med. 1978 May 4;298(18):981–987. doi: 10.1056/NEJM197805042981801. [DOI] [PubMed] [Google Scholar]
- Merskey C. Defibrination syndrome or? Blood. 1973 Apr;41(4):599–603. [PubMed] [Google Scholar]
- Miles L. A., Plow E. F., Donnelly K. J., Hougie C., Griffin J. H. A bleeding disorder due to deficiency of alpha 2-antiplasmin. Blood. 1982 Jun;59(6):1246–1251. [PubMed] [Google Scholar]
- Milner P. F. Oxygen transport in sickle cell anemia. Arch Intern Med. 1974 Apr;133(4):565–572. [PubMed] [Google Scholar]
- Miner M. E., Kaufman H. H., Graham S. H., Haar F. H., Gildenberg P. L. Disseminated intravascular coagulation fibrinolytic syndrome following head injury in children: frequency and prognostic implications. J Pediatr. 1982 May;100(5):687–691. doi: 10.1016/s0022-3476(82)80565-9. [DOI] [PubMed] [Google Scholar]
- Miser A. W., Miser J. S., Clark B. S. Continuous intravenous infusion of morphine sulfate for control of severe pain in children with terminal malignancy. J Pediatr. 1980 May;96(5):930–932. doi: 10.1016/s0022-3476(80)80585-3. [DOI] [PubMed] [Google Scholar]
- Morrison J. C., Foster H. Transfusion therapy in pregnant patients with sickle-cell disease: a National Institutes of Health consensus development conference. Ann Intern Med. 1979 Jul;91(1):122–123. doi: 10.7326/0003-4819-91-1-122. [DOI] [PubMed] [Google Scholar]
- Morrison J. C., Whybrew W. D., Bucovaz E. T. Use of partial exchange transfusion preoperatively in patients with sickle cell hemoglobinopathies. Am J Obstet Gynecol. 1978 Sep 1;132(1):59–63. doi: 10.1016/0002-9378(78)90799-8. [DOI] [PubMed] [Google Scholar]
- Morrison J. C., Wiser W. L. The use of prophylactic partial exchange tranfusion in pregnancies associated with sickle cell hemoglobinopathies. Obstet Gynecol. 1976 Nov;48(5):516–520. [PubMed] [Google Scholar]
- Murano G. The "Hageman" connection: interrelationships of blood coagulation, fibrino(geno)lysis, kinin generation, and complement activation. Am J Hematol. 1978;4(4):409–417. doi: 10.1002/ajh.2830040412. [DOI] [PubMed] [Google Scholar]
- Nachman J. B., Honig G. R. Fever and neutropenia in children with neoplastic disease: an analysis of 158 episodes. Cancer. 1980 Jan 15;45(2):407–412. doi: 10.1002/1097-0142(19800115)45:2<407::aid-cncr2820450237>3.0.co;2-s. [DOI] [PubMed] [Google Scholar]
- Nauseef W. M., Maki D. G. A study of the value of simple protective isolation in patients with granulocytopenia. N Engl J Med. 1981 Feb 19;304(8):448–453. doi: 10.1056/NEJM198102193040802. [DOI] [PubMed] [Google Scholar]
- Negus D., Friedgood A., Cox S. J., Peel A. L., Wells B. W. Ultra-low dose intravenous heparin in the prevention of postoperative deep-vein thrombosis. Lancet. 1980 Apr 26;1(8174):891–894. doi: 10.1016/s0140-6736(80)90834-x. [DOI] [PubMed] [Google Scholar]
- Newburger P. E., Sallan S. E. Chronic pain: principles of management. J Pediatr. 1981 Feb;98(2):180–189. doi: 10.1016/s0022-3476(81)80632-4. [DOI] [PubMed] [Google Scholar]
- Nilsson I. M., Holmberg L. Von Willebrand's disease today. Clin Haematol. 1979 Feb;8(1):147–168. [PubMed] [Google Scholar]
- Nilsson I. M., Lamme S. On acquired hemophilia A. A survey of 11 cases. Acta Med Scand. 1980;208(1-2):5–12. [PubMed] [Google Scholar]
- O'Brien R. T., McIntosh S., Aspnes G. T., Pearson H. A. Prospective study of sickle cell anemia in infancy. J Pediatr. 1976 Aug;89(2):205–210. doi: 10.1016/s0022-3476(76)80449-0. [DOI] [PubMed] [Google Scholar]
- O'Grady J., Bunting S., Moncada S. Antithrombotic drugs in relation to prostaglandin metabolism. Clin Haematol. 1980 Oct;9(3):535–555. [PubMed] [Google Scholar]
- O'Regan S., Carson S., Chesney R. W., Drummond K. N. Electrolyte and acid-base disturbances in the management of leukemia. Blood. 1977 Mar;49(3):345–353. [PubMed] [Google Scholar]
- OWEN D. M., ALDRIDGE J. E., THOMPSON R. B. AN UNUSUAL HEPATIC SEQUELA OF SICKLE CELL ANEMIA: A REPORT OF FIVE CASES. Am J Med Sci. 1965 Feb;249:175–185. doi: 10.1097/00000441-196502000-00006. [DOI] [PubMed] [Google Scholar]
- Orenstein W. A., Heymann D. L., Ellis R. J., Rosenberg R. L., Nakano J., Halsey N. A., Overturf G. D., Hayden G. F., Witte J. J. Prophylaxis of varicella in high-risk children: dose-response effect of zoster immune globulin. J Pediatr. 1981 Mar;98(3):368–373. doi: 10.1016/s0022-3476(81)80697-x. [DOI] [PubMed] [Google Scholar]
- Packham M. A., Mustard J. F. Clinical pharmacology of platelets. Blood. 1977 Oct;50(4):555–573. [PubMed] [Google Scholar]
- Patel A. R., Shah P. C., Rhee H. L., Sassoon H., Rao K. P. Cyclophosphamide therapy and interstitial pulmonary fibrosis. Cancer. 1976 Oct;38(4):1542–1549. doi: 10.1002/1097-0142(197610)38:4<1542::aid-cncr2820380416>3.0.co;2-r. [DOI] [PubMed] [Google Scholar]
- Pearson H. A., Cornelius E. A., Schwartz A. D., Zelson J. H., Wolfson S. L., Spencer R. P. Transfusion-reversible functional asplenia in young children with sickle-cell anemia. N Engl J Med. 1970 Aug 13;283(7):334–337. doi: 10.1056/NEJM197008132830703. [DOI] [PubMed] [Google Scholar]
- Pearson H. A., McIntosh S., Ritchey A. K., Lobel J. S., Rooks Y., Johnston D. Developmental aspects of splenic function in sickle cell diseases. Blood. 1979 Mar;53(3):358–365. [PubMed] [Google Scholar]
- Pearson H. A. Sickle cell anemia and severe infections due to encapsulated bacteria. J Infect Dis. 1977 Aug;136 (Suppl):S25–S30. doi: 10.1093/infdis/136.supplement.s25. [DOI] [PubMed] [Google Scholar]
- Pearson H. A., Spencer R. P., Cornelius E. A. Functional asplenia in sickle-cell anemia. N Engl J Med. 1969 Oct 23;281(17):923–926. doi: 10.1056/NEJM196910232811703. [DOI] [PubMed] [Google Scholar]
- Pegelow C., Goldberg R., Turkel S., Powars D. Severe coagulation abnormalities in Reye syndrome. J Pediatr. 1977 Sep;91(3):413–416. doi: 10.1016/s0022-3476(77)81310-3. [DOI] [PubMed] [Google Scholar]
- Penner J. A. Hypercoagulation and thrombosis. Med Clin North Am. 1980 Jul;64(4):743–759. doi: 10.1016/s0025-7125(16)31591-7. [DOI] [PubMed] [Google Scholar]
- Petch M. C., Serjeant G. R. Clinical features of pulmonary lesions in sickle-cell anaemia. Br Med J. 1970 Jul 4;3(5713):31–31. doi: 10.1136/bmj.3.5713.31. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pineo G. F., Gallus A. S., Hirsh J. Unexpected vitamin K deficiency in hospitalized patients. Can Med Assoc J. 1973 Nov 3;109(9):880–883. [PMC free article] [PubMed] [Google Scholar]
- Pinkel D. The ninth annual David Karnofsky Lecture. Treatment of acute lymphocytic leukemia. Cancer. 1979 Mar;43(3):1128–1137. doi: 10.1002/1097-0142(197903)43:3<1128::aid-cncr2820430352>3.0.co;2-y. [DOI] [PubMed] [Google Scholar]
- Pochedly C. Neurotoxicity due to CNS therapy for leukemia. Med Pediatr Oncol. 1977;3(1):101–115. doi: 10.1002/mpo.2950030114. [DOI] [PubMed] [Google Scholar]
- Powars D. R. Natural history of sickle cell disease--the first ten years. Semin Hematol. 1975 Jul;12(3):267–285. [PubMed] [Google Scholar]
- Powars D. R., Pegelow C. H. The spleen in sickle cell disease and thalassemia. Am J Pediatr Hematol Oncol. 1979 Winter;1(4):343–353. [PubMed] [Google Scholar]
- Powars D., Overturf G., Turner E. Is there an increased risk of Haemophilus influenzae septicemia in children with sickle cell anemia? Pediatrics. 1983 Jun;71(6):927–931. [PubMed] [Google Scholar]
- Powars D., Wilson B., Imbus C., Pegelow C., Allen J. The natural history of stroke in sickle cell disease. Am J Med. 1978 Sep;65(3):461–471. doi: 10.1016/0002-9343(78)90772-6. [DOI] [PubMed] [Google Scholar]
- Price R. A., Birdwell D. A. The central nervous system in childhood leukemia. III. Mineralizing microangiopathy and dystrophic calcification. Cancer. 1978 Aug;42(2):717–728. doi: 10.1002/1097-0142(197808)42:2<717::aid-cncr2820420244>3.0.co;2-3. [DOI] [PubMed] [Google Scholar]
- Prober C. G., Kirk L. E., Keeney R. E. Acyclovir therapy of chickenpox in immunosuppressed children--a collaborative study. J Pediatr. 1982 Oct;101(4):622–625. doi: 10.1016/s0022-3476(82)80725-7. [DOI] [PubMed] [Google Scholar]
- Rabiner S. F., Molinas F. The role of phenol and phenolic acids on the thrombocytopathy and defective platelet aggregation of patients with renal failure. Am J Med. 1970 Sep;49(3):346–351. doi: 10.1016/s0002-9343(70)80026-2. [DOI] [PubMed] [Google Scholar]
- Rajani K., Goetzman B. W., Wennberg R. P., Turner E., Abildgaard C. Effect of heparinization of fluids infused through an umbilical artery catheter on catheter patency and frequency of complications. Pediatrics. 1979 Apr;63(4):552–556. [PubMed] [Google Scholar]
- Ramsay N. K., Brown D. M., Nesbit M. E., Coccia P. F., Krivit W., Krutzik S. Autonomous production of parathyroid hormone by lymphoblastic leukemia cells in culture. J Pediatr. 1979 Apr;94(4):623–625. doi: 10.1016/s0022-3476(79)80034-7. [DOI] [PubMed] [Google Scholar]
- Ramsay N. K., Coccia P. F., Krivit W., Nesbit M. E., Edson J. R. The effect of L-asparaginase of plasma coagulation factors in acute lymphoblastic leukemia. Cancer. 1977 Oct;40(4):1398–1401. doi: 10.1002/1097-0142(197710)40:4<1398::aid-cncr2820400406>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
- Ranney H. M. Interactions of other hemoglobin variants with sickle-cell hemoglobin. N Engl J Med. 1970 Dec 24;283(26):1462–1463. doi: 10.1056/NEJM197012242832610. [DOI] [PubMed] [Google Scholar]
- Rao A. K., Walsh P. N. Acquired qualitative platelet disorders. Clin Haematol. 1983 Feb;12(1):201–238. [PubMed] [Google Scholar]
- Ritchey A. K., Andiman W., McIntosh S., Berman B., Luce D. Mononucleosis syndrome following granulocyte transfusion in patients with leukemia. J Pediatr. 1980 Aug;97(2):267–269. doi: 10.1016/s0022-3476(80)80492-6. [DOI] [PubMed] [Google Scholar]
- Rizza C. R., Biggs R. The treatment of patients who have factor-VIII antibodies. Br J Haematol. 1973 Jan;24(1):65–82. doi: 10.1111/j.1365-2141.1973.tb05728.x. [DOI] [PubMed] [Google Scholar]
- Rogers D. W., Clarke J. M., Cupidore L., Ramlal A. M., Sparke B. R., Serjeant G. R. Early deaths in Jamaican children with sickle cell disease. Br Med J. 1978 Jun 10;1(6126):1515–1516. doi: 10.1136/bmj.1.6126.1515. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rosen R. C., Huestis D. W., Corrigan J. J., Jr Acute leukemia and granulocyte transfusion: Fatal graft-versus-host reaction following transfusion of cells obtained from normal donors. J Pediatr. 1978 Aug;93(2):268–270. doi: 10.1016/s0022-3476(78)80517-4. [DOI] [PubMed] [Google Scholar]
- Rosenberg R. D. Biologic actions of heparin. Semin Hematol. 1977 Oct;14(4):427–440. [PubMed] [Google Scholar]
- Rosse W. F. Treatment of chronic immune thrombocytopenia. Clin Haematol. 1983 Feb;12(1):267–284. [PubMed] [Google Scholar]
- Roth J. A., Cukingnan R. A., Scott C. R. Use of activated coagulation time to monitor heparin during cardiac surgery. Ann Thorac Surg. 1979 Jul;28(1):69–72. doi: 10.1016/s0003-4975(10)63396-6. [DOI] [PubMed] [Google Scholar]
- Rubinstein L. J., Herman M. M., Long T. F., Wilbur J. R. Disseminated necrotizing leukoencephalopathy: a complication of treated central nervous system leukemia and lymphoma. Cancer. 1975 Feb;35(2):291–305. doi: 10.1002/1097-0142(197502)35:2<291::aid-cncr2820350202>3.0.co;2-v. [DOI] [PubMed] [Google Scholar]
- Russell M. O., Goldberg H. I., Reis L., Friedman S., Slater R., Reivich M., Schwartz E. Transfusion therapy for cerebrovascular abnormalities in sickle cell disease. J Pediatr. 1976 Mar;88(3):382–387. doi: 10.1016/s0022-3476(76)80251-x. [DOI] [PubMed] [Google Scholar]
- SHAPIRO N. D., POE M. F. Sickle-cell disease: an anesthesiological problem. Anesthesiology. 1955 Sep;16(5):771–780. doi: 10.1097/00000542-195509000-00017. [DOI] [PubMed] [Google Scholar]
- Salzman E. W., Deykin D., Shapiro R. M., Rosenberg R. Management of heparin therapy: Controlled prospective trial. N Engl J Med. 1975 May 15;292(20):1046–1050. doi: 10.1056/NEJM197505152922002. [DOI] [PubMed] [Google Scholar]
- Sarnaik S. A., Lusher J. M. Neurological complications of sickle cell anemia. Am J Pediatr Hematol Oncol. 1982 Winter;4(4):386–394. doi: 10.1097/00043426-198224000-00006. [DOI] [PubMed] [Google Scholar]
- Scanlon J. W., Krakaur R. Hyperkalemia following exchange transfusion. J Pediatr. 1980 Jan;96(1):108–110. doi: 10.1016/s0022-3476(80)80342-8. [DOI] [PubMed] [Google Scholar]
- Schmidt W. F., 3rd, Kim H. C., Tomassini N., Schwartz E. RBC destruction caused by a micropore blood filter. JAMA. 1982 Oct 1;248(13):1629–1632. [PubMed] [Google Scholar]
- Seeler R. A., Royal J. E., Powe L., Goldberg H. R. Moyamoya in children with sickle cell anemia and cerebrovascular occlusion. J Pediatr. 1978 Nov;93(5):808–810. doi: 10.1016/s0022-3476(78)81086-5. [DOI] [PubMed] [Google Scholar]
- Seligsohn U. High gene frequency of factor XI (PTA) deficiency in Ashkenazi Jews. Blood. 1978 Jun;51(6):1223–1228. [PubMed] [Google Scholar]
- Sell E. J., Corrigan J. J., Jr Platelet counts, fibrinogen concentrations, and factor V and factor VIII levels in healthy infants according to gestational age. J Pediatr. 1973 Jun;82(6):1028–1032. doi: 10.1016/s0022-3476(73)80436-6. [DOI] [PubMed] [Google Scholar]
- Shalev O., Silverberg R. Dexamethasone for acute radiation encephalopathy. Lancet. 1978 Sep 9;2(8089):574–575. doi: 10.1016/s0140-6736(78)92905-7. [DOI] [PubMed] [Google Scholar]
- Shapiro S. S. Antibodies to blood coagulation factors. Clin Haematol. 1979 Feb;8(1):207–214. [PubMed] [Google Scholar]
- Sharma G. V., Cella G., Parisi A. F., Sasahara A. A. Thrombolytic therapy. N Engl J Med. 1982 May 27;306(21):1268–1276. doi: 10.1056/NEJM198205273062105. [DOI] [PubMed] [Google Scholar]
- Shulman N. R., Hirschman R. J. Acquired hemophilia. Trans Assoc Am Physicians. 1969;82:388–397. [PubMed] [Google Scholar]
- Shulman S. T., Bartlett J., Clyde W. A., Jr, Ayoub E. M. The unusual severity of Mycoplasmal pneumonia in children with sickle-cell disease. N Engl J Med. 1972 Jul 27;287(4):164–167. doi: 10.1056/NEJM197207272870403. [DOI] [PubMed] [Google Scholar]
- Singsen B. H. Plasmapheresis: a pediatric perspective. J Pediatr. 1981 Feb;98(2):232–235. doi: 10.1016/s0022-3476(81)80641-5. [DOI] [PubMed] [Google Scholar]
- Sixma J. J., Wester J. The hemostatic plug. Semin Hematol. 1977 Jul;14(3):265–299. [PubMed] [Google Scholar]
- Sjamsoedin L. J., Heijnen L., Mauser-Bunschoten E. P., van Geijlswijk J. L., van Houwelingen H., van Asten P., Sixma J. J. The effect of activated prothrombin-complex concentrate (FEIBA) on joint and muscle bleeding in patients with hemophilia A and antibodies to factor VIII. A double-blind clinical trial. N Engl J Med. 1981 Sep 24;305(13):717–721. doi: 10.1056/NEJM198109243051301. [DOI] [PubMed] [Google Scholar]
- Smith J. K., Bidwell E. Therapeutic materials used in the treatment of coagulation defects. Clin Haematol. 1979 Feb;8(1):183–206. [PubMed] [Google Scholar]
- Snyder E. L., Bookbinder M. Role of microaggregate blood filtration in clinical medicine. Transfusion. 1983 Nov-Dec;23(6):460–470. doi: 10.1046/j.1537-2995.1983.23684074264.x. [DOI] [PubMed] [Google Scholar]
- Snyder E. L., Hezzey A., Barash P. G., Palermo G. Microaggregate blood filtration in patients with compromised pulmonary function. Transfusion. 1982 Jan-Feb;22(1):21–25. doi: 10.1046/j.1537-2995.1982.22182154209.x. [DOI] [PubMed] [Google Scholar]
- Snyder E., Underwood P., Spivack M. Administration of microaggregate filtered blood using a manual infusion pump. Transfusion. 1980 Mar-Apr;20(2):145–152. doi: 10.1046/j.1537-2995.1980.20280169954.x. [DOI] [PubMed] [Google Scholar]
- Solanki D., McCurdy P. R. Delayed hemolytic transfusion reactions. An often-missed entity. JAMA. 1978 Feb 20;239(8):729–731. [PubMed] [Google Scholar]
- Speck W. T. Acquired immune deficiency syndrome. J Pediatr. 1983 Jul;103(1):161–163. doi: 10.1016/s0022-3476(83)80806-3. [DOI] [PubMed] [Google Scholar]
- Steele R. W., Myers M. G., Vincent M. M. Transfer factor for the prevention of varicella-zoster infection in childhood leukemia. N Engl J Med. 1980 Aug 14;303(7):355–359. doi: 10.1056/NEJM198008143030702. [DOI] [PubMed] [Google Scholar]
- Steiner R. W., Coggins C., Carvalho A. C. Bleeding time in uremia: a useful test to assess clinical bleeding. Am J Hematol. 1979;7(2):107–117. doi: 10.1002/ajh.2830070203. [DOI] [PubMed] [Google Scholar]
- Steinherz P. G., Reich L. M. Granulocyte transfusions in infected neutropenic children with malignancies. Med Pediatr Oncol. 1979;6(1):65–76. doi: 10.1002/mpo.2950060110. [DOI] [PubMed] [Google Scholar]
- Stewart J. H., Castaldi P. A. Uraemic bleeding: a reversible platelet defect corrected by dialysis. Q J Med. 1967 Jul;36(143):409–423. [PubMed] [Google Scholar]
- Stockman J. A., Nigro M. A., Mishkin M. M., Oski F. A. Occlusion of large cerebral vessels in sickle-cell anemia. N Engl J Med. 1972 Oct 26;287(17):846–849. doi: 10.1056/NEJM197210262871703. [DOI] [PubMed] [Google Scholar]
- Stuart M. J. Inherited defects of platelet function. Semin Hematol. 1975 Jul;12(3):233–253. [PubMed] [Google Scholar]
- Stuart M. J. Platelet function in the neonate. Am J Pediatr Hematol Oncol. 1979 Fall;1(3):227–234. doi: 10.1097/00043426-197923000-00006. [DOI] [PubMed] [Google Scholar]
- Sullivan J. M., Harken D. E., Gorlin R. Pharmacologic control of thromboembolic complications of cardiac-valve replacement. N Engl J Med. 1971 Jun 24;284(25):1391–1394. doi: 10.1056/NEJM197106242842501. [DOI] [PubMed] [Google Scholar]
- Talarico L., Weintraub L. R. Leukocytic fibrinolysis in myelomonocytic leukemia. Cancer. 1977 Apr;39(4):1618–1624. doi: 10.1002/1097-0142(197704)39:4<1618::aid-cncr2820390436>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
- Thomas D. P. Heparin in the prophylaxis and treatment of venous thromboembolism. Semin Hematol. 1978 Jan;15(1):1–17. [PubMed] [Google Scholar]
- Thompson J. S., Severson C. D., Parmely M. J., Marmorstein B. L., Simmons A. Pulmonary "hypersensitivity" reactions induced by transfusion of non-HL-A leukoagglutinins. N Engl J Med. 1971 May 20;284(20):1120–1125. doi: 10.1056/NEJM197105202842003. [DOI] [PubMed] [Google Scholar]
- Todres I. D., Reppert S. M., Walker P. F., Grillo H. C. Mangement of critical airway obstruction in a child with a mediastinal tumor. Anesthesiology. 1976 Jul;45(1):100–102. doi: 10.1097/00000542-197607000-00020. [DOI] [PubMed] [Google Scholar]
- Vermylen J., Badenhorst P. N., Deckmyn H., Arnout J. Normal mechanisms of platelet function. Clin Haematol. 1983 Feb;12(1):107–151. [PubMed] [Google Scholar]
- Verstraete M. Biochemical and clinical aspects of thrombolysis. Semin Hematol. 1978 Jan;15(1):35–54. [PubMed] [Google Scholar]
- Walden P. A., Dent J., Bagshawe K. D. Fatal hypoglycemia after cytotoxic chemotherapy: a report of two cases and a review of the literature. Cancer. 1979 Dec;44(6):2029–2031. doi: 10.1002/1097-0142(197912)44:6<2029::aid-cncr2820440611>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
- Waldman J. D., Czapek E. E., Paul M. H., Schwartz A. D., Levin D. L., Schindler S. Shortened platelet survival in cyanotic heart disease. J Pediatr. 1975 Jul;87(1):77–79. doi: 10.1016/s0022-3476(75)80073-4. [DOI] [PubMed] [Google Scholar]
- Walker B. K., Ballas S. K., Burka E. R. The diagnosis of pulmonary thromboembolism in sickle cell disease. Am J Hematol. 1979;7(3):219–232. doi: 10.1002/ajh.2830070305. [DOI] [PubMed] [Google Scholar]
- Walzer P. D., Perl D. P., Krogstad D. J., Rawson P. G., Schultz M. G. Pneumocystis carinii pneumonia in the United States. Epidemiologic, diagnostic, and clinical features. Ann Intern Med. 1974 Jan;80(1):83–93. doi: 10.7326/0003-4819-80-1-83. [DOI] [PubMed] [Google Scholar]
- Wedemeyer A. L., Lewis J. H. Improvement in hemostasis following phlebotomy in cyanotic patients with heart disease. J Pediatr. 1973 Jul;83(1):46–50. doi: 10.1016/s0022-3476(73)80311-7. [DOI] [PubMed] [Google Scholar]
- Weiss H. J. Antiplatelet therapy (first of two parts). N Engl J Med. 1978 Jun 15;298(24):1344–1347. doi: 10.1056/NEJM197806152982405. [DOI] [PubMed] [Google Scholar]
- Weiss H. J. Platelet physiology and abnormalities of platelet function (first of two parts). N Engl J Med. 1975 Sep 11;293(11):531–541. doi: 10.1056/NEJM197509112931105. [DOI] [PubMed] [Google Scholar]
- Weller T. H. Varicella and herpes zoster. Changing concepts of the natural history, control, and importance of a not-so-benign virus. N Engl J Med. 1983 Dec 8;309(23):1434–1440. doi: 10.1056/NEJM198312083092306. [DOI] [PubMed] [Google Scholar]
- Wells R. J., Weetman R. M., Baehner R. L. The impact of isolated central nervous system relapse following initial complete remission in childhood acute lymphocytic leukemia. J Pediatr. 1980 Sep;97(3):429–432. doi: 10.1016/s0022-3476(80)80196-x. [DOI] [PubMed] [Google Scholar]
- Wenz B., Barland P. Therapeutic intensive plasmapheresis. Semin Hematol. 1981 Apr;18(2):147–162. [PubMed] [Google Scholar]
- Wessler S., Gitel S. N. Heparin: new concepts relevant to clinical use. Blood. 1979 Apr;53(4):525–544. [PubMed] [Google Scholar]
- White G. C., 2nd, McMillan C. W., Blatt P. M., Roberts H. R. Factor VIII inhibitors: a clinical overview. Am J Hematol. 1982 Dec;13(4):335–342. doi: 10.1002/ajh.2830130410. [DOI] [PubMed] [Google Scholar]
- White G. C., 2nd, Taylor R. E., Blatt P. M., Roberts H. R. Treatment of a high titer anti-factor-VIII antibody by continuous factor VIII administration: report of a case. Blood. 1983 Jul;62(1):141–145. [PubMed] [Google Scholar]
- Whitley R. J., Ch'ien L. T., Dolin R., Galasso G. J., Alford C. A., Jr Adenine arabinoside therapy of herpes zoster in the immunosuppressed. NIAID collaborative antiviral study. N Engl J Med. 1976 May 27;294(22):1193–1199. doi: 10.1056/NEJM197605272942201. [DOI] [PubMed] [Google Scholar]
- Whitley R., Hilty M., Haynes R., Bryson Y., Connor J. D., Soong S. J., Alford C. A. Vidarabine therapy of varicella in immunosuppressed patients. J Pediatr. 1982 Jul;101(1):125–131. doi: 10.1016/s0022-3476(82)80201-1. [DOI] [PubMed] [Google Scholar]
- Wilimas J., Goff J. R., Anderson H. R., Jr, Langston J. W., Thompson E. Efficacy of transfusion therapy for one to two years in patients with sickle cell disease and cerebrovascular accidents. J Pediatr. 1980 Feb;96(2):205–208. doi: 10.1016/s0022-3476(80)80803-1. [DOI] [PubMed] [Google Scholar]
- Wilson C. B. Current concepts in cancer: brain tumors. N Engl J Med. 1979 Jun 28;300(26):1469–1471. doi: 10.1056/NEJM197906283002605. [DOI] [PubMed] [Google Scholar]
- Wilson D., Stewart A., Szwed J., Einhorn L. H. Cardiac arrest due to hyperkalemia following therapy for acute lymphoblastic leukemia. Cancer. 1977 May;39(5):2290–2293. doi: 10.1002/1097-0142(197705)39:5<2290::aid-cncr2820390550>3.0.co;2-p. [DOI] [PubMed] [Google Scholar]
- Winkelstein J. A., Drachman R. H. Deficiency of pneumococcal serum opsonizing activity in sickle-cell disease. N Engl J Med. 1968 Aug 29;279(9):459–466. doi: 10.1056/NEJM196808292790904. [DOI] [PubMed] [Google Scholar]
- Wolff L. J., Bartlett M. S., Baehner R. L., Grosfeld J. L., Smith J. W. The causes of interstitial pneumonitis in immunocompromised children: an aggressive systematic approach to diagnosis. Pediatrics. 1977 Jul;60(1):41–45. [PubMed] [Google Scholar]
- Wolk J. A., Stuart M. J., Stockman J. A., 3rd, Oski F. A. Neutropenia, fever, and infection in children with acute lymphocytic leukemia. Am J Dis Child. 1977 Feb;131(2):157–158. doi: 10.1001/archpedi.1977.02120150039007. [DOI] [PubMed] [Google Scholar]
- Wood D. H. Cerebrovascular complications of sickle cell anemia. Stroke. 1978 Jan-Feb;9(1):73–75. doi: 10.1161/01.str.9.1.73. [DOI] [PubMed] [Google Scholar]
- Zimmerman T. S., Ruggeri Z. M. von Willebrand's Disease. Clin Haematol. 1983 Feb;12(1):175–200. [PubMed] [Google Scholar]
- Zipursky A., deSa D., Hsu E., Johnston M., Milner R. Clinical and laboratory diagnosis of hemostatic disorders in newborn infants. Am J Pediatr Hematol Oncol. 1979 Fall;1(3):217–226. doi: 10.1097/00043426-197923000-00005. [DOI] [PubMed] [Google Scholar]
- Zusman J., Brown D. M., Nesbit M. E. Hyperphosphatemia, hyperphosphaturia and hypocalcemia in acute lymphoblastic leukemia. N Engl J Med. 1973 Dec 20;289(25):1335–1340. doi: 10.1056/NEJM197312202892503. [DOI] [PubMed] [Google Scholar]




