Abstract
An American physician-traveler to East Africa presented with manifestations of cerebral malaria and was treated with intravenous quinidine for chloroquine-resistant falciparum malaria. He later relapsed with Plasmodium ovale infection, despite previous primaquine therapy. Treatment of chloroquine-resistant malaria is discussed. The difficulty in diagnosing P. ovale infections and the predominance of this malaria species over P. vivax in East Africa are reviewed.
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- Bia F. J., Barry M. Parasitic infections of the central nervous system. Neurol Clin. 1986 Feb;4(1):171–206. [PubMed] [Google Scholar]
- Bruce-Chwatt L. J. Terminology of relapsing malaria: enigma variations. Trans R Soc Trop Med Hyg. 1984;78(6):844–845. doi: 10.1016/0035-9203(84)90042-7. [DOI] [PubMed] [Google Scholar]
- Centers for Disease Control (CDC) Imported malaria among travelers--United States. MMWR Morb Mortal Wkly Rep. 1984 Jul 13;33(27):388–390. [PubMed] [Google Scholar]
- Centers for Disease Control (CDC) Revised recommendations for preventing malaria in travelers to areas with chloroquine-resistant Plasmodium falciparum. MMWR Morb Mortal Wkly Rep. 1985 Apr 12;34(14):185-90, 195. [PubMed] [Google Scholar]
- Centers for Disease Control (CDC) Update: chloroquine-resistant Plasmodium falciparum--Africa. MMWR Morb Mortal Wkly Rep. 1983 Aug 26;32(33):437–438. [PubMed] [Google Scholar]
- Chin W., Coatney G. R. Relapse activity in sporozoite-induced infections with a West African strain of Plasmodium ovale. Am J Trop Med Hyg. 1971 Nov;20(6):825–827. doi: 10.4269/ajtmh.1971.20.825. [DOI] [PubMed] [Google Scholar]
- Harwin R. M. Malaria due to Plasmodium ovale in Rhodesia. Cent Afr J Med. 1971 Jul;17(7):146–148. [PubMed] [Google Scholar]
- Lysenko A. J., Beljaev A. E. An analysis of the geographical distribution of Plasmodium ovale. Bull World Health Organ. 1969;40(3):383–394. [PMC free article] [PubMed] [Google Scholar]
- Miller L. H., Mason S. J., Clyde D. F., McGinniss M. H. The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy. N Engl J Med. 1976 Aug 5;295(6):302–304. doi: 10.1056/NEJM197608052950602. [DOI] [PubMed] [Google Scholar]
- Phillips R. E., Warrell D. A., White N. J., Looareesuwan S., Karbwang J. Intravenous quinidine for the treatment of severe falciparum malaria. Clinical and pharmacokinetic studies. N Engl J Med. 1985 May 16;312(20):1273–1278. doi: 10.1056/NEJM198505163122001. [DOI] [PubMed] [Google Scholar]
- Weniger B. G., Blumberg R. S., Campbell C. C., Jones T. C., Mount D. L., Friedman S. M. High-level chloroquine resistance of Plasmodium falciparum malaria acquired in Kenya. N Engl J Med. 1982 Dec 16;307(25):1560–1562. doi: 10.1056/NEJM198212163072506. [DOI] [PubMed] [Google Scholar]
- White N. J., Looareesuwan S., Warrell D. A., Chongsuphajaisiddhi T., Bunnag D., Harinasuta T. Quinidine in falciparum malaria. Lancet. 1981 Nov 14;2(8255):1069–1071. doi: 10.1016/s0140-6736(81)91275-7. [DOI] [PubMed] [Google Scholar]
- White N. J., Looareesuwan S., Warrell D. A. Quinine and quinidine: a comparison of EKG effects during the treatment of malaria. J Cardiovasc Pharmacol. 1983 Mar-Apr;5(2):173–175. doi: 10.1097/00005344-198303000-00001. [DOI] [PubMed] [Google Scholar]
- Wyler D. J. Malaria--resurgence, resistance, and research (second of two parts). N Engl J Med. 1983 Apr 21;308(16):934–940. doi: 10.1056/NEJM198304213081605. [DOI] [PubMed] [Google Scholar]