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. 1986 May-Jun;59(3):257–265.

The cardiac filling pressure following exercise and thermal stress.

K A Kirsch, L Röcker, H von Ameln, K Hrynyschyn
PMCID: PMC2590149  PMID: 3751134

Abstract

Under heat stress, a decrease of the central venous pressure (CVP) was regularly observed, raising the question of whether this reaction is a limiting factor for the circulation. In animal experiments it could be shown, however, that despite a lowered CVP, which depended on the elevated body temperatures, a high cardiac output (CO), as well as an elevated stroke volume could be maintained. A low CVP went hand in hand with a low total peripheral resistance. It was argued that under these circumstances the low CVP was not limiting because the intrinsic factors of the heart (sympathetic stimulation) were capable of maintaining a high CO. In human experiments the lowered CVP had to be seen in relation to the degree of dehydration. Regardless of whether the plasma volume remained constant, as in exercise, or declined, as in thermal stress (sauna), the CVP followed the volume depletion of the vascular and extravascular space, and it might well be that under these circumstances CVP is limiting. In this case, however, the altered CVP must be seen first as a monitor for the fluid deficit and not as a factor controlling cardiac function.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ekelund L. G. Circulatory and respiratory adaptation during prolonged exercise. Acta Physiol Scand Suppl. 1967;292:1–38. [PubMed] [Google Scholar]
  2. GAUER O. H., HENRY J. P. Circulatory basis of fluid volume control. Physiol Rev. 1963 Jul;43:423–481. doi: 10.1152/physrev.1963.43.3.423. [DOI] [PubMed] [Google Scholar]
  3. GAUER O. H., HENRY J. P., SIEKER H. O. Changes in central venous pressure after moderate hemorrhage and transfusion in man. Circ Res. 1956 Jan;4(1):79–84. doi: 10.1161/01.res.4.1.79. [DOI] [PubMed] [Google Scholar]
  4. GAUER O. H., SIEKER H. O. The continuous recording of central venous pressure changes from an arm vein. Circ Res. 1956 Jan;4(1):74–78. doi: 10.1161/01.res.4.1.74. [DOI] [PubMed] [Google Scholar]
  5. GAUER O. H., THRON H. L. Properties of veins in vivo: integrated effects of their smooth muscle. Physiol Rev Suppl. 1962 Jul;5:283–308. [PubMed] [Google Scholar]
  6. HAMMEL H. T., WYNDHAM C. H., HARDY J. D. Heat production and heat loss in the dog at 8-36 degrees C environmental temperature. Am J Physiol. 1958 Jul;194(1):99–108. doi: 10.1152/ajplegacy.1958.194.1.99. [DOI] [PubMed] [Google Scholar]
  7. HENRY J. P., GAUER O. H. The influence of temperature upon venous pressure in the foot. J Clin Invest. 1950 Jul;29(7):855–861. doi: 10.1172/JCI102318. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Horstman D. H., Horvath S. M. Cardiovascular adjustments to progressive dehydration. J Appl Physiol. 1973 Oct;35(4):501–504. doi: 10.1152/jappl.1973.35.4.501. [DOI] [PubMed] [Google Scholar]
  9. Iriki M., Riedel W., Simon E. Regional differentiation of sympathetic activity during hypothalamic heating and cooling in anesthetized rabbits. Pflugers Arch. 1971;328(4):320–331. doi: 10.1007/BF00586834. [DOI] [PubMed] [Google Scholar]
  10. KOZLOWSKI S., SALTIN B. EFFECT OF SWEAT LOSS ON BODY FLUIDS. J Appl Physiol. 1964 Nov;19:1119–1124. doi: 10.1152/jappl.1964.19.6.1119. [DOI] [PubMed] [Google Scholar]
  11. Kirsch K., Hrynyschyn K., Ameln H., Röcker L., Wicke H. J. Extracellular fluid volume and central circulation after long lasting exercise and dehydration in conscious dogs. Pflugers Arch. 1977 Apr 25;368(3):209–215. doi: 10.1007/BF00585198. [DOI] [PubMed] [Google Scholar]
  12. Kirsch K., Schultze G., Röcker L., Bierbaum U., Eckert P. The effect of exercise and dehydration on plasma volume and central venous pressure. Z Kardiol. 1973 Jan;62(1):49–58. [PubMed] [Google Scholar]
  13. Nadel E. R. Recent advances in temperature regulation during exercise in humans. Fed Proc. 1985 Apr;44(7):2286–2292. [PubMed] [Google Scholar]
  14. Rothe C. F. Reflex control of veins and vascular capacitance. Physiol Rev. 1983 Oct;63(4):1281–1342. doi: 10.1152/physrev.1983.63.4.1281. [DOI] [PubMed] [Google Scholar]
  15. Rowell L. B., Brengelmann G. L., Blackmon J. R., Murray J. A. Redistribution of blood flow during sustained high skin temperature in resting man. J Appl Physiol. 1970 Apr;28(4):415–420. doi: 10.1152/jappl.1970.28.4.415. [DOI] [PubMed] [Google Scholar]
  16. Rowell L. B., Brengelmann G. L., Detry J. M., Wyss C. Venomotor responses to rapid changes in skin temperature in exercising man. J Appl Physiol. 1971 Jan;30(1):64–71. doi: 10.1152/jappl.1971.30.1.64. [DOI] [PubMed] [Google Scholar]
  17. Rowell L. B. Cardiovascular aspects of human thermoregulation. Circ Res. 1983 Apr;52(4):367–379. doi: 10.1161/01.res.52.4.367. [DOI] [PubMed] [Google Scholar]
  18. Rowell L. B. Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev. 1974 Jan;54(1):75–159. doi: 10.1152/physrev.1974.54.1.75. [DOI] [PubMed] [Google Scholar]
  19. Rowell L. B., Marx H. J., Bruce R. A., Conn R. D., Kusumi F. Reductions in cardiac output, central blood volume, and stroke volume with thermal stress in normal men during exercise. J Clin Invest. 1966 Nov;45(11):1801–1816. doi: 10.1172/JCI105484. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. SALTIN B. AEROBIC AND ANAEROBIC WORK CAPACITY AFTER DEHYDRATION. J Appl Physiol. 1964 Nov;19:1114–1118. doi: 10.1152/jappl.1964.19.6.1114. [DOI] [PubMed] [Google Scholar]
  21. SALTIN B. CIRCULATORY RESPONSE TO SUBMAXIMAL AND MAXIMAL EXERCISE AFTER THERMAL DEHYDRATION. J Appl Physiol. 1964 Nov;19:1125–1132. doi: 10.1152/jappl.1964.19.6.1125. [DOI] [PubMed] [Google Scholar]
  22. Wyndham C. H., Benade A. J., Williams C. G., Strydom N. B., Goldin A., Heyns A. J. Changes in central circulation and body fluid spaces during acclimatization to heat. J Appl Physiol. 1968 Nov;25(5):586–593. doi: 10.1152/jappl.1968.25.5.586. [DOI] [PubMed] [Google Scholar]

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