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. 1988 May-Jun;61(3):215–222.

Human T-cell lymphotropic virus type I and adult T-cell leukemia/lymphoma outside Japan and the Caribbean Basin.

P H Levine 1, E S Jaffe 1, A Manns 1, E L Murphy 1, J Clark 1, W A Blattner 1
PMCID: PMC2590467  PMID: 3262954

Abstract

Ninety-six patients with the diagnosis of adult T-cell leukemia/lymphoma (ATLL) were identified in countries outside Japan and the Caribbean Basin. Seventy-four of these patients were initially diagnosed in the United States; 25 of 52 patients whose places of birth were known had been born in the United States. The detection of 14 patients born in the southeastern United States, all black, indicates a group deserving particular attention for studies of human T-cell lymphotropic virus type I (HTLV-I), a suspected etiologic agent in most cases of ATLL. Although geographic clustering of ATLL in areas endemic for HTLV-I, particularly southwest Japan and the Caribbean Basin, is a dramatic feature of this disease, a review of the literature indicates that HTLV-I-associated ATLL probably occurs sporadically in a much wider distribution, the disease being diagnosed in native-born African, Chinese, European, and Latin American patients. A registry for ATLL cases is suggested, to assist in the identification of risk factors for this disease and, at the same time, improve case definitions and early diagnosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Blayney D. W., Blattner W. A., Robert-Guroff M., Jaffe E. S., Fisher R. I., Bunn P. A., Jr, Patton M. G., Rarick H. R., Gallo R. C. The human T-cell leukemia-lymphoma virus in the southeastern United States. JAMA. 1983 Aug 26;250(8):1048–1052. [PubMed] [Google Scholar]
  2. Blayney D. W., Jaffe E. S., Fisher R. I., Schechter G. P., Cossman J., Robert-Guroff M., Kalyanaraman V. S., Blattner W. A., Gallo R. C. The human T-cell leukemia/lymphoma virus, lymphoma, lytic bone lesions, and hypercalcemia. Ann Intern Med. 1983 Feb;98(2):144–151. doi: 10.7326/0003-4819-98-2-144. [DOI] [PubMed] [Google Scholar]
  3. Catovsky D., Greaves M. F., Rose M., Galton D. A., Goolden A. W., McCluskey D. R., White J. M., Lampert I., Bourikas G., Ireland R. Adult T-cell lymphoma-leukaemia in Blacks from the West Indies. Lancet. 1982 Mar 20;1(8273):639–643. doi: 10.1016/s0140-6736(82)92200-0. [DOI] [PubMed] [Google Scholar]
  4. Gessain A., Barin F., Vernant J. C., Gout O., Maurs L., Calender A., de Thé G. Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis. Lancet. 1985 Aug 24;2(8452):407–410. doi: 10.1016/s0140-6736(85)92734-5. [DOI] [PubMed] [Google Scholar]
  5. Gibbs W. N., Lofters W. S., Campbell M., Hanchard B., LaGrenade L., Cranston B., Hendriks J., Jaffe E. S., Saxinger C., Robert-Guroff M. Non-Hodgkin lymphoma in Jamaica and its relation to adult T-cell leukemia-lymphoma. Ann Intern Med. 1987 Mar;106(3):361–368. doi: 10.7326/0003-4819-106-3-361. [DOI] [PubMed] [Google Scholar]
  6. Greaves M. F., Verbi W., Tilley R., Lister T. A., Habeshaw J., Guo H. G., Trainor C. D., Robert-Guroff M., Blattner W., Reitz M. Human T-cell leukemia virus (HTLV) in the United Kingdom. Int J Cancer. 1984 Jun 15;33(6):795–806. doi: 10.1002/ijc.2910330614. [DOI] [PubMed] [Google Scholar]
  7. Hino S., Yamaguchi K., Katamine S., Sugiyama H., Amagasaki T., Kinoshita K., Yoshida Y., Doi H., Tsuji Y., Miyamoto T. Mother-to-child transmission of human T-cell leukemia virus type-I. Jpn J Cancer Res. 1985 Jun;76(6):474–480. [PubMed] [Google Scholar]
  8. Jaffe E. S., Blattner W. A., Blayney D. W., Bunn P. A., Jr, Cossman J., Robert-Guroff M., Gallo R. C. The pathologic spectrum of adult T-cell leukemia/lymphoma in the United States. Human T-cell leukemia/lymphoma virus-associated lymphoid malignancies. Am J Surg Pathol. 1984 Apr;8(4):263–275. doi: 10.1097/00000478-198404000-00003. [DOI] [PubMed] [Google Scholar]
  9. Kinoshita K., Amagasaki T., Hino S., Doi H., Yamanouchi K., Ban N., Momita S., Ikeda S., Kamihira S., Ichimaru M. Milk-borne transmission of HTLV-I from carrier mothers to their children. Jpn J Cancer Res. 1987 Jul;78(7):674–680. [PubMed] [Google Scholar]
  10. Kinoshita K., Hino S., Amagaski T., Ikeda S., Yamada Y., Suzuyama J., Momita S., Toriya K., Kamihira S., Ichimaru M. Demonstration of adult T-cell leukemia virus antigen in milk from three sero-positive mothers. Gan. 1984 Feb;75(2):103–105. [PubMed] [Google Scholar]
  11. Kuo T. T., Chan H. L., Su I. J., Eimoto T., Maeda Y., Kikuchi M., Chen M. J., Kuan Y. Z., Chen W. J., Sun C. F. Serological survey of antibodies to the adult T-cell leukemia virus-associated antigen (HTLV-A) in Taiwan. Int J Cancer. 1985 Sep 15;36(3):345–348. [PubMed] [Google Scholar]
  12. Okochi K., Sato H., Hinuma Y. A retrospective study on transmission of adult T cell leukemia virus by blood transfusion: seroconversion in recipients. Vox Sang. 1984;46(5):245–253. doi: 10.1111/j.1423-0410.1984.tb00083.x. [DOI] [PubMed] [Google Scholar]
  13. Osame M., Matsumoto M., Usuku K., Izumo S., Ijichi N., Amitani H., Tara M., Igata A. Chronic progressive myelopathy associated with elevated antibodies to human T-lymphotropic virus type I and adult T-cell leukemialike cells. Ann Neurol. 1987 Feb;21(2):117–122. doi: 10.1002/ana.410210203. [DOI] [PubMed] [Google Scholar]
  14. Pandolfi F., Manzari V., De Rossi G., Semenzato G., Lauria F., Liso V., Ranucci A., Pizzolo G., Barillari G., Aiuti F. T-helper phenotype chronic lymphocytic leukaemia and "adult T-cell leukaemia" in Italy. Endemic HTLV-I-related T-cell leukaemias in southern Europe. Lancet. 1985 Sep 21;2(8456):633–636. doi: 10.1016/s0140-6736(85)90004-2. [DOI] [PubMed] [Google Scholar]
  15. Robert-Guroff M., Nakao Y., Notake K., Ito Y., Sliski A., Gallo R. C. Natural antibodies to human retrovirus HTLV in a cluster of Japanese patients with adult T cell leukemia. Science. 1982 Feb 19;215(4535):975–978. doi: 10.1126/science.6760397. [DOI] [PubMed] [Google Scholar]
  16. Robert-Guroff M., Weiss S. H., Giron J. A., Jennings A. M., Ginzburg H. M., Margolis I. B., Blattner W. A., Gallo R. C. Prevalence of antibodies to HTLV-I, -II, and -III in intravenous drug abusers from an AIDS endemic region. JAMA. 1986 Jun 13;255(22):3133–3137. [PubMed] [Google Scholar]
  17. Román G. C. Retrovirus-associated myelopathies. Arch Neurol. 1987 Jun;44(6):659–663. doi: 10.1001/archneur.1987.00520180073022. [DOI] [PubMed] [Google Scholar]
  18. Sato H., Okochi K. Transmission of human T-cell leukemia virus (HTLV-I) by blood transfusion: demonstration of proviral DNA in recipients' blood lymphocytes. Int J Cancer. 1986 Mar 15;37(3):395–400. doi: 10.1002/ijc.2910370311. [DOI] [PubMed] [Google Scholar]
  19. Su I. J., Chan H. L., Kuo T. T., Eimoto T., Maeda Y., Kikuchi M., Kuan Y. Z., Shih L. Y., Chen M. J., Takeshita M. Adult T-cell leukemia/lymphoma in Taiwan. A clinicopathologic observation. Cancer. 1985 Nov 1;56(9):2217–2220. doi: 10.1002/1097-0142(19851101)56:9<2217::aid-cncr2820560914>3.0.co;2-5. [DOI] [PubMed] [Google Scholar]
  20. Tajima K., Kuroishi T. Estimation of rate of incidence of ATL among ATLV (HTLV-I) carriers in Kyushu, Japan. Jpn J Clin Oncol. 1985 Jun;15(2):423–430. [PubMed] [Google Scholar]
  21. Tajima K., Tominaga S., Suchi T., Kawagoe T., Komoda H., Hinuma Y., Oda T., Fujita K. Epidemiological analysis of the distribution of antibody to adult T-cell leukemia-virus-associated antigen: possible horizontal transmission of adult T-cell leukemia virus. Gan. 1982 Dec;73(6):893–901. [PubMed] [Google Scholar]
  22. Uchiyama T., Yodoi J., Sagawa K., Takatsuki K., Uchino H. Adult T-cell leukemia: clinical and hematologic features of 16 cases. Blood. 1977 Sep;50(3):481–492. [PubMed] [Google Scholar]
  23. Usuku K., Sonoda S., Osame M., Yashiki S., Takahashi K., Matsumoto M., Sawada T., Tsuji K., Tara M., Igata A. HLA haplotype-linked high immune responsiveness against HTLV-I in HTLV-I-associated myelopathy: comparison with adult T-cell leukemia/lymphoma. Ann Neurol. 1988;23 (Suppl):S143–S150. doi: 10.1002/ana.410230733. [DOI] [PubMed] [Google Scholar]
  24. Williams C. K., Alabi G. O., Junaid T. A., Saxinger C., Gallo R. C., Blayney D. W., Blattner W. A., Greaves M. F. Human T cell leukaemia virus associated lymphoproliferative disease: report of two cases in Nigeria. Br Med J (Clin Res Ed) 1984 May 19;288(6429):1495–1496. doi: 10.1136/bmj.288.6429.1495. [DOI] [PMC free article] [PubMed] [Google Scholar]

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