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. 1994 Jan-Apr;67(1-2):15–21.

How long can we live?

S C Finch 1
PMCID: PMC2590795  PMID: 7645309

Abstract

The continuing rapid age shift in recent years from predominately a younger to an older population in America and many other countries is a problem of great concern. Its socioeconomic implications for the distant future are quite unpredictable due to our inability to answer a few basic questions. How long will life expectancy continue to increase? What is the maximum possible length of life?

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bidder G. P. SENESCENCE. Br Med J. 1932 Sep 24;2(3742):583–585. doi: 10.1136/bmj.2.3742.583. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Chandra R. K. Effect of vitamin and trace-element supplementation on immune responses and infection in elderly subjects. Lancet. 1992 Nov 7;340(8828):1124–1127. doi: 10.1016/0140-6736(92)93151-c. [DOI] [PubMed] [Google Scholar]
  3. Clarfield A. M. My quest for eternal youth. CMAJ. 1990 May 15;142(10):1118–1119. [PMC free article] [PubMed] [Google Scholar]
  4. Feinendegen L. E., Mühlensiepen H., Bond V. P., Sondhaus C. A. Intracellular stimulation of biochemical control mechanisms by low-dose, low-LET irradiation. Health Phys. 1987 May;52(5):663–669. doi: 10.1097/00004032-198705000-00020. [DOI] [PubMed] [Google Scholar]
  5. Gruenberg E. M. The failures of success. Milbank Mem Fund Q Health Soc. 1977 Winter;55(1):3–24. [PubMed] [Google Scholar]
  6. HAYFLICK L., MOORHEAD P. S. The serial cultivation of human diploid cell strains. Exp Cell Res. 1961 Dec;25:585–621. doi: 10.1016/0014-4827(61)90192-6. [DOI] [PubMed] [Google Scholar]
  7. HAYFLICK L. THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS. Exp Cell Res. 1965 Mar;37:614–636. doi: 10.1016/0014-4827(65)90211-9. [DOI] [PubMed] [Google Scholar]
  8. Hayflick L. Why do we live so long? Geriatrics. 1988 Oct;43(10):77-9, 82, 87. [PubMed] [Google Scholar]
  9. Katz S., Branch L. G., Branson M. H., Papsidero J. A., Beck J. C., Greer D. S. Active life expectancy. N Engl J Med. 1983 Nov 17;309(20):1218–1224. doi: 10.1056/NEJM198311173092005. [DOI] [PubMed] [Google Scholar]
  10. Kondo S. Altruistic cell suicide in relation to radiation hormesis. Int J Radiat Biol Relat Stud Phys Chem Med. 1988 Jan;53(1):95–102. doi: 10.1080/09553008814550461. [DOI] [PubMed] [Google Scholar]
  11. Leaf A. Getting old. Sci Am. 1973 Sep;229(3):44–52. doi: 10.1038/scientificamerican0973-44. [DOI] [PubMed] [Google Scholar]
  12. Martin G. R., Danner D. B., Holbrook N. J. Aging--causes and defenses. Annu Rev Med. 1993;44:419–429. doi: 10.1146/annurev.me.44.020193.002223. [DOI] [PubMed] [Google Scholar]
  13. Olshansky S. J., Carnes B. A., Cassel C. In search of Methuselah: estimating the upper limits to human longevity. Science. 1990 Nov 2;250(4981):634–640. doi: 10.1126/science.2237414. [DOI] [PubMed] [Google Scholar]
  14. Olshansky S. J. The human life span: are we reaching the outer limits? Geriatrics. 1993 Mar;48(3):85–88. [PubMed] [Google Scholar]
  15. Rimm E. B., Stampfer M. J., Ascherio A., Giovannucci E., Colditz G. A., Willett W. C. Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med. 1993 May 20;328(20):1450–1456. doi: 10.1056/NEJM199305203282004. [DOI] [PubMed] [Google Scholar]
  16. Rudman D., Feller A. G., Nagraj H. S., Gergans G. A., Lalitha P. Y., Goldberg A. F., Schlenker R. A., Cohn L., Rudman I. W., Mattson D. E. Effects of human growth hormone in men over 60 years old. N Engl J Med. 1990 Jul 5;323(1):1–6. doi: 10.1056/NEJM199007053230101. [DOI] [PubMed] [Google Scholar]
  17. Sagan L. A. On radiation, paradigms, and hormesis. Science. 1989 Aug 11;245(4918):574–621. doi: 10.1126/science.2669125. [DOI] [PubMed] [Google Scholar]
  18. Stampfer M. J., Hennekens C. H., Manson J. E., Colditz G. A., Rosner B., Willett W. C. Vitamin E consumption and the risk of coronary disease in women. N Engl J Med. 1993 May 20;328(20):1444–1449. doi: 10.1056/NEJM199305203282003. [DOI] [PubMed] [Google Scholar]
  19. Wolff S. Are radiation-induced effects hormetic? Science. 1989 Aug 11;245(4918):575–621. doi: 10.1126/science.2762808. [DOI] [PubMed] [Google Scholar]

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