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. 2008 Dec;14(12):2538–2549. doi: 10.1261/rna.1253408

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FIGURE 4. — Response of the SFSR3 gene promoter to β-catenin/TCF4 transcriptional activity. (Left side) Drawing showing the 1982-bp genomic fragment containing the SRp20 gene promoter that was subcloned to yield the luciferase reporter construct pRep5 and derived deletion mutants. (Gray shaded area) The responsive promoter region between nucleotides −225 and −1282. (Right side) The reporters' transcriptional activities in response to stimulation by βCat-CA or to inhibition by TCF-DN are also shown as diagrams for each individual construct and are given as fold-increase in luciferase activity compared to the control pEGFP vector.