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. 1991 Dec;59(12):4684–4686. doi: 10.1128/iai.59.12.4684-4686.1991

Gamma interferon-activated human macrophages and Toxoplasma gondii, Chlamydia psittaci, and Leishmania donovani: antimicrobial role of limiting intracellular iron.

H W Murray 1, A M Granger 1, R F Teitelbaum 1
PMCID: PMC259098  PMID: 1937829

Abstract

Iron-saturated transferrin did not reverse the intracellular killing or inhibition of Toxoplasma gondii, Chlamydia psittaci, or Leishmania donovani by gamma interferon-activated human macrophages. Deferoxamine, an iron chelator, also did not impair replication within unstimulated macrophages. Limiting the availability of intracellular iron is an unlikely mechanism in human macrophage activity against these three diverse pathogens.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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