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. 1991 Dec;59(12):4729–4731. doi: 10.1128/iai.59.12.4729-4731.1991

Interleukin-1 administration to C3H/HeJ mice after but not prior to infection increases resistance to Salmonella typhimurium.

P J Morrissey 1, K Charrier 1
PMCID: PMC259108  PMID: 1937834

Abstract

Interleukin-1 (IL-1) treatment of C3H/HeN and C3H/HeJ mice prior to infection with Salmonella typhimurium increased the survival fraction only in C3H/HeN mice. IL-1 administration after infection resulted in a significant increase in mean survival time in C3H/HeJ but not C3H/HeN mice. Bacterial growth in IL-1-treated C3H/HeJ mice was less than that in control mice.

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Selected References

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