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. 1988 Jan;56(1):1–6. doi: 10.1128/iai.56.1.1-6.1988

Maternal immunization with P fimbriae for the prevention of neonatal pyelonephritis.

M B Kaack 1, J A Roberts 1, G Baskin 1, G M Patterson 1
PMCID: PMC259223  PMID: 2891616

Abstract

Rhesus monkeys (Macaca mulatta) were immunized with purified P fimbriae from Escherichia coli during the last trimester of pregnancy. Infants born of these mothers were compared with those from nonimmunized rhesus mothers. A delay in the onset of renal disease after bladder infection showed protection from passive immunization. This was associated with a high antibody titer in serum. In addition to delayed onset of renal infection, a decreased number of immunized monkeys developed pyelonephritis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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