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. Author manuscript; available in PMC: 2008 Dec 2.
Published in final edited form as: Biochemistry. 2007 Aug 9;46(35):10192–10201. doi: 10.1021/bi7003476

Table 5.

Optimized parameters for most plausible Model #14c (see Table 4 and Scheme 2 for model description). The limiting values were computed at 90% confidence level, by using the profile-t method of Bates & Watts (30).

Reaction Parameter Best-fit value Std. Error Lower limit Upper limit
2PP2 Kd1, µM 0.038 ± 0.052 0.0013 0.28
P + RPR Kd2, µM 0.021 ± 0.011 0.0044 0.041
PR + PP2R Kd3, µM 0.37 ± 0.12 0.19 1.9
2PRP2R2 Kd4, µM 0.041 ± 0.019 0.0036 0.070
PRproduct kcat, min−1 10.6 ± 0.6 9.7 11.9