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. 2003 Mar;95(3):188–195.

Adequate nutrient intake can reduce cardiovascular disease risk in African Americans.

Molly E Reusser 1, Douglas B DiRienzo 1, Gregory D Miller 1, David A McCarron 1
PMCID: PMC2594417  PMID: 12749678

Abstract

Cardiovascular disease kills nearly as many Americans each year as the next seven leading causes of death combined. The prevalence of cardiovascular disease and most of its associated risk factors is markedly higher and increasing more rapidly among African Americans than in any other racial or ethnic group. Improving these statistics may be simply a matter of improving diet quality. In recent years, a substantial and growing body of evidence has revealed that dietary patterns complete in all food groups, including nutrient-rich dairy products, are essential for preventing and reducing cardiovascular disease and the conditions that contribute to it. Several cardiovascular risk factors, including hypertension, insulin resistance syndrome, and obesity, have been shown to be positively influenced by dietary patterns that include adequate intake of dairy products. The benefits of nutrient-rich dietary patterns have been specifically tested in randomized, controlled trials emphasizing African American populations. These studies demonstrated proportionally greater benefits for African Americans without evidence of adverse effects such as symptoms of lactose intolerance. As currently promoted for the prevention of certain cancers and osteoporosis, regular consumption of diets that meet recommended nutrient intake levels might also be the most effective approach for reducing cardiovascular disease risk in African Americans.

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Selected References

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  1. Appel L. J., Moore T. J., Obarzanek E., Vollmer W. M., Svetkey L. P., Sacks F. M., Bray G. A., Vogt T. M., Cutler J. A., Windhauser M. M. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med. 1997 Apr 17;336(16):1117–1124. doi: 10.1056/NEJM199704173361601. [DOI] [PubMed] [Google Scholar]
  2. Birkett N. J. Comments on a meta-analysis of the relation between dietary calcium intake and blood pressure. Am J Epidemiol. 1998 Aug 1;148(3):223–233. doi: 10.1093/oxfordjournals.aje.a009627. [DOI] [PubMed] [Google Scholar]
  3. Bucher H. C., Cook R. J., Guyatt G. H., Lang J. D., Cook D. J., Hatala R., Hunt D. L. Effects of dietary calcium supplementation on blood pressure. A meta-analysis of randomized controlled trials. JAMA. 1996 Apr 3;275(13):1016–1022. doi: 10.1001/jama.1996.03530370054031. [DOI] [PubMed] [Google Scholar]
  4. Buchowski Maciej S., Semenya Joyce, Johnson Abiodun O. Dietary calcium intake in lactose maldigesting intolerant and tolerant African-American women. J Am Coll Nutr. 2002 Feb;21(1):47–54. doi: 10.1080/07315724.2002.10719193. [DOI] [PubMed] [Google Scholar]
  5. Davies K. M., Heaney R. P., Recker R. R., Lappe J. M., Barger-Lux M. J., Rafferty K., Hinders S. Calcium intake and body weight. J Clin Endocrinol Metab. 2000 Dec;85(12):4635–4638. doi: 10.1210/jcem.85.12.7063. [DOI] [PubMed] [Google Scholar]
  6. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001 May 16;285(19):2486–2497. doi: 10.1001/jama.285.19.2486. [DOI] [PubMed] [Google Scholar]
  7. Griffith L. E., Guyatt G. H., Cook R. J., Bucher H. C., Cook D. J. The influence of dietary and nondietary calcium supplementation on blood pressure: an updated metaanalysis of randomized controlled trials. Am J Hypertens. 1999 Jan;12(1 Pt 1):84–92. doi: 10.1016/s0895-7061(98)00224-6. [DOI] [PubMed] [Google Scholar]
  8. Hatton D. C., McCarron D. A. Dietary calcium and blood pressure in experimental models of hypertension. A review. Hypertension. 1994 Apr;23(4):513–530. doi: 10.1161/01.hyp.23.4.513. [DOI] [PubMed] [Google Scholar]
  9. Heaney R. P. Calcium, dairy products and osteoporosis. J Am Coll Nutr. 2000 Apr;19(2 Suppl):83S–99S. doi: 10.1080/07315724.2000.10718088. [DOI] [PubMed] [Google Scholar]
  10. Huijbregts P., Feskens E., Räsänen L., Fidanza F., Nissinen A., Menotti A., Kromhout D. Dietary pattern and 20 year mortality in elderly men in Finland, Italy, and The Netherlands: longitudinal cohort study. BMJ. 1997 Jul 5;315(7099):13–17. doi: 10.1136/bmj.315.7099.13. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Jackson K. A., Savaiano D. A. Lactose maldigestion, calcium intake and osteoporosis in African-, Asian-, and Hispanic-Americans. J Am Coll Nutr. 2001 Apr;20(2 Suppl):198S–207S. doi: 10.1080/07315724.2001.10719032. [DOI] [PubMed] [Google Scholar]
  12. Jarvis Judith K., Miller Gregory D. Overcoming the barrier of lactose intolerance to reduce health disparities. J Natl Med Assoc. 2002 Feb;94(2):55–66. [PMC free article] [PubMed] [Google Scholar]
  13. Kant A. K., Schatzkin A., Graubard B. I., Schairer C. A prospective study of diet quality and mortality in women. JAMA. 2000 Apr 26;283(16):2109–2115. doi: 10.1001/jama.283.16.2109. [DOI] [PubMed] [Google Scholar]
  14. Krauss R. M., Deckelbaum R. J., Ernst N., Fisher E., Howard B. V., Knopp R. H., Kotchen T., Lichtenstein A. H., McGill H. C., Pearson T. A. Dietary guidelines for healthy American adults. A statement for health professionals from the Nutrition Committee, American Heart Association. Circulation. 1996 Oct 1;94(7):1795–1800. doi: 10.1161/01.cir.94.7.1795. [DOI] [PubMed] [Google Scholar]
  15. Krauss R. M., Eckel R. H., Howard B., Appel L. J., Daniels S. R., Deckelbaum R. J., Erdman J. W., Jr, Kris-Etherton P., Goldberg I. J., Kotchen T. A. AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation. 2000 Oct 31;102(18):2284–2299. doi: 10.1161/01.cir.102.18.2284. [DOI] [PubMed] [Google Scholar]
  16. Lin Y. C., Lyle R. M., McCabe L. D., McCabe G. P., Weaver C. M., Teegarden D. Dairy calcium is related to changes in body composition during a two-year exercise intervention in young women. J Am Coll Nutr. 2000 Nov-Dec;19(6):754–760. doi: 10.1080/07315724.2000.10718075. [DOI] [PubMed] [Google Scholar]
  17. Logan A. G. The DASH trials implicate dysfunction in calcium regulation in the pathogenesis of human hypertension. Curr Hypertens Rep. 2001 Oct;3(5):367–370. doi: 10.1007/s11906-001-0050-6. [DOI] [PubMed] [Google Scholar]
  18. Massey L. K. Dairy food consumption, blood pressure and stroke. J Nutr. 2001 Jul;131(7):1875–1878. doi: 10.1093/jn/131.7.1875. [DOI] [PubMed] [Google Scholar]
  19. McCarron D. A. Calcium metabolism and hypertension. Kidney Int. 1989 Feb;35(2):717–736. doi: 10.1038/ki.1989.44. [DOI] [PubMed] [Google Scholar]
  20. McCarron D. A. Diet and blood pressure--the paradigm shift. Science. 1998 Aug 14;281(5379):933–934. doi: 10.1126/science.281.5379.933. [DOI] [PubMed] [Google Scholar]
  21. McCarron D. A., Morris C. D., Cole C. Dietary calcium in human hypertension. Science. 1982 Jul 16;217(4556):267–269. doi: 10.1126/science.7089566. [DOI] [PubMed] [Google Scholar]
  22. McCarron D. A., Morris C. D., Henry H. J., Stanton J. L. Blood pressure and nutrient intake in the United States. Science. 1984 Jun 29;224(4656):1392–1398. doi: 10.1126/science.6729459. [DOI] [PubMed] [Google Scholar]
  23. Miller G. D., DiRienzo D. D., Reusser M. E., McCarron D. A. Benefits of dairy product consumption on blood pressure in humans: a summary of the biomedical literature. J Am Coll Nutr. 2000 Apr;19(2 Suppl):147S–164S. doi: 10.1080/07315724.2000.10718085. [DOI] [PubMed] [Google Scholar]
  24. Miller G. D., Jarvis J. K., McBean L. D. The importance of meeting calcium needs with foods. J Am Coll Nutr. 2001 Apr;20(2 Suppl):168S–185S. doi: 10.1080/07315724.2001.10719029. [DOI] [PubMed] [Google Scholar]
  25. Mokdad A. H., Bowman B. A., Ford E. S., Vinicor F., Marks J. S., Koplan J. P. The continuing epidemics of obesity and diabetes in the United States. JAMA. 2001 Sep 12;286(10):1195–1200. doi: 10.1001/jama.286.10.1195. [DOI] [PubMed] [Google Scholar]
  26. Mokdad A. H., Serdula M. K., Dietz W. H., Bowman B. A., Marks J. S., Koplan J. P. The spread of the obesity epidemic in the United States, 1991-1998. JAMA. 1999 Oct 27;282(16):1519–1522. doi: 10.1001/jama.282.16.1519. [DOI] [PubMed] [Google Scholar]
  27. Patel Y. T., Minocha A. Lactose intolerance: diagnosis and management. Compr Ther. 2000 Winter;26(4):246–250. doi: 10.1007/s12019-000-0025-6. [DOI] [PubMed] [Google Scholar]
  28. Pereira Mark A., Jacobs David R., Jr, Van Horn Linda, Slattery Martha L., Kartashov Alex I., Ludwig David S. Dairy consumption, obesity, and the insulin resistance syndrome in young adults: the CARDIA Study. JAMA. 2002 Apr 24;287(16):2081–2089. doi: 10.1001/jama.287.16.2081. [DOI] [PubMed] [Google Scholar]
  29. Pi-Sunyer F. X. Health implications of obesity. Am J Clin Nutr. 1991 Jun;53(6 Suppl):1595S–1603S. doi: 10.1093/ajcn/53.6.1595S. [DOI] [PubMed] [Google Scholar]
  30. Power M. L., Heaney R. P., Kalkwarf H. J., Pitkin R. M., Repke J. T., Tsang R. C., Schulkin J. The role of calcium in health and disease. Am J Obstet Gynecol. 1999 Dec;181(6):1560–1569. doi: 10.1016/s0002-9378(99)70404-7. [DOI] [PubMed] [Google Scholar]
  31. Pribila B. A., Hertzler S. R., Martin B. R., Weaver C. M., Savaiano D. A. Improved lactose digestion and intolerance among African-American adolescent girls fed a dairy-rich diet. J Am Diet Assoc. 2000 May;100(5):524–530. doi: 10.1016/S0002-8223(00)00162-0. [DOI] [PubMed] [Google Scholar]
  32. Reaven Gerald. Syndrome X. Curr Treat Options Cardiovasc Med. 2001 Aug;3(4):323–332. doi: 10.1007/s11936-001-0094-6. [DOI] [PubMed] [Google Scholar]
  33. Reed D., McGee D., Yano K., Hankin J. Diet, blood pressure, and multicollinearity. Hypertension. 1985 May-Jun;7(3 Pt 1):405–410. [PubMed] [Google Scholar]
  34. Sacks F. M., Obarzanek E., Windhauser M. M., Svetkey L. P., Vollmer W. M., McCullough M., Karanja N., Lin P. H., Steele P., Proschan M. A. Rationale and design of the Dietary Approaches to Stop Hypertension trial (DASH). A multicenter controlled-feeding study of dietary patterns to lower blood pressure. Ann Epidemiol. 1995 Mar;5(2):108–118. doi: 10.1016/1047-2797(94)00055-x. [DOI] [PubMed] [Google Scholar]
  35. Sacks F. M., Svetkey L. P., Vollmer W. M., Appel L. J., Bray G. A., Harsha D., Obarzanek E., Conlin P. R., Miller E. R., 3rd, Simons-Morton D. G. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N Engl J Med. 2001 Jan 4;344(1):3–10. doi: 10.1056/NEJM200101043440101. [DOI] [PubMed] [Google Scholar]
  36. Suarez F. L., Adshead J., Furne J. K., Levitt M. D. Lactose maldigestion is not an impediment to the intake of 1500 mg calcium daily as dairy products. Am J Clin Nutr. 1998 Nov;68(5):1118–1122. doi: 10.1093/ajcn/68.5.1118. [DOI] [PubMed] [Google Scholar]
  37. Svetkey L. P., Simons-Morton D., Vollmer W. M., Appel L. J., Conlin P. R., Ryan D. H., Ard J., Kennedy B. M. Effects of dietary patterns on blood pressure: subgroup analysis of the Dietary Approaches to Stop Hypertension (DASH) randomized clinical trial. Arch Intern Med. 1999 Feb 8;159(3):285–293. doi: 10.1001/archinte.159.3.285. [DOI] [PubMed] [Google Scholar]
  38. Vesa T. H., Marteau P., Korpela R. Lactose intolerance. J Am Coll Nutr. 2000 Apr;19(2 Suppl):165S–175S. doi: 10.1080/07315724.2000.10718086. [DOI] [PubMed] [Google Scholar]
  39. Young E. W., Bukoski R. D., McCarron D. A. Calcium metabolism in experimental hypertension. Proc Soc Exp Biol Med. 1988 Feb;187(2):123–141. doi: 10.3181/00379727-187-42646. [DOI] [PubMed] [Google Scholar]
  40. Zemel M. B., Shi H., Greer B., Dirienzo D., Zemel P. C. Regulation of adiposity by dietary calcium. FASEB J. 2000 Jun;14(9):1132–1138. [PubMed] [Google Scholar]

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