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. 1976 Nov;49(5):439–445.

Evaluation of the Epidemic Potential of Western Equine Encephalitis Virus in the Northeastern United States 1,2

Robert C Wallis, Curtis G Hayes
PMCID: PMC2595287  PMID: 1035448

Abstract

The problem of evaluating the epidemic potential of western equine encephalitis in the northeastern United States is presented and possible reasons are discussed for the present lack of human and horse cases of this disease even though increased numbers of isolations of the virus have been obtained in the East during recent years. Epidemiologic factors of vector bionomics and virus strain variations are considered. It is concluded that while this virus strain can no longer be regarded as uncommon in the Northeast, the evidence indicates there is little potential for epidemic expression of this agent in the human and horse population. This appears to be due to differences in the bionomics of the mosquito Culiseta melanura, which serves as the primary enzootic vector in the northeastern United States and in the bionomics of Culex tarsalis that is the vector in the western region of the United States. Other limiting factors in the epidemic potential may be variations between virus strains located in the East and West.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CASALS J. ANTIGENIC VARIANTS OF EASTERN EQUINE ENCEPHALITIS VIRUS. J Exp Med. 1964 Apr 1;119:547–565. doi: 10.1084/jem.119.4.547. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CHAMBERLAIN R. W., KISSLING R. E., STAMM D. D., SUDIA W. D. Transmission of eastern equine encephalitis to horses by Aedes sollicitans mosquitoes. Am J Trop Med Hyg. 1956 Sep;5(5):802–808. doi: 10.4269/ajtmh.1956.5.802. [DOI] [PubMed] [Google Scholar]
  3. CHAMBERLAIN R. W., SIKES R. K., NELSON D. B., SUDIA W. D. Studies on the North American arthropod-borne encephalitides. VI. Quantitative determinations of virus-vector relationships. Am J Hyg. 1954 Nov;60(3):278–285. doi: 10.1093/oxfordjournals.aje.a119721. [DOI] [PubMed] [Google Scholar]
  4. Chamberlain R. W., Sudia W. D., Coleman P. H., Johnston J. G., Jr, Work T. H. Arbovirus isolations from mosquitoes collected in Waycross, Georgia, 1963, during an outbreak of equine encephalitis. Am J Epidemiol. 1969 Jan;89(1):82–88. doi: 10.1093/oxfordjournals.aje.a120918. [DOI] [PubMed] [Google Scholar]
  5. Edman J. D., Webber L. A., Kale H. W., 2nd Host-feeding patterns of Florida mosquitoes. II. Culiseta. J Med Entomol. 1972 Sep 30;9(5):429–434. doi: 10.1093/jmedent/9.5.429. [DOI] [PubMed] [Google Scholar]
  6. Feemster R. F., Getting V. A. Distribution of the Vectors of Equine Encephalomyelitis in Massachusetts. Am J Public Health Nations Health. 1941 Aug;31(8):791–802. doi: 10.2105/ajph.31.8.791. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. HAYES R. O., DANIELS J. B., MACCREADY R. A. Western encephalitis virus in Massachusetts. Proc Soc Exp Biol Med. 1961 Dec;108:805–808. doi: 10.3181/00379727-108-27074. [DOI] [PubMed] [Google Scholar]
  8. HENDERSON J. R. IMMUNOLOGIC CHARACTERIZATION OF WESTERN EQUINE ENCEPHALOMYELITIS VIRUS STRAINS. J Immunol. 1964 Sep;93:452–461. [PubMed] [Google Scholar]
  9. HENDERSON J. R., SHAH H. H., WALLIS R. C. ANTIGENIC VARIANTS OF ARBOVIRUSES. I. THE HOST AS A DETERMINANT IN THE EVOLVEMENT OF STRAIN VARIANTS. Virology. 1965 Jun;26:326–332. doi: 10.1016/0042-6822(65)90280-1. [DOI] [PubMed] [Google Scholar]
  10. HOLDEN P. Recovery of western equine encephalomyelitis virus from naturally infected English sparrows of New Jersey, 1953. Proc Soc Exp Biol Med. 1955 Mar;88(3):490–492. doi: 10.3181/00379727-88-21629. [DOI] [PubMed] [Google Scholar]
  11. Henderson J. R., Levine S. I., Stim T. B., Karabatsos N. Antigenic variants of arboviruses. 3. Host passage selection of constituent antigen subpopulations of strains. J Immunol. 1967 Nov;99(5):935–944. [PubMed] [Google Scholar]
  12. Howard J. J., Wallis R. C. Infection and transmission of eastern equine encephalomyelitis virus with colonized Culiseta melanura (Coquillett). Am J Trop Med Hyg. 1974 May;23(3):522–525. doi: 10.4269/ajtmh.1974.23.522. [DOI] [PubMed] [Google Scholar]
  13. KARABATSOS N., BOURKE A. T., HENDERSON J. R. ANTIGENIC VARIATION AMONG STRAINS OF WESTERN EQUINE ENCEPHALOMYELITIS VIRUS. Am J Trop Med Hyg. 1963 May;12:408–412. doi: 10.4269/ajtmh.1963.12.408. [DOI] [PubMed] [Google Scholar]
  14. LeDuc J. W., Suyemoto W., Eldridge B. F., Saugstad E. S. Ecology of arboviruses in a Maryland freshwater swamp. II. Blood feeding patterns of potential mosquito vectors. Am J Epidemiol. 1972 Aug;96(2):123–128. doi: 10.1093/oxfordjournals.aje.a121438. [DOI] [PubMed] [Google Scholar]
  15. McGowan J. E., Jr, Bryan J. A., Gregg M. B. Surveillance of arboviral encephalitis in the United States, 1955-1971. Am J Epidemiol. 1973 Mar;97(3):199–207. doi: 10.1093/oxfordjournals.aje.a121500. [DOI] [PubMed] [Google Scholar]
  16. Means R. G. Host preferences of mosquitoes (Diptera: culicidae) in Suffolk County, New York. Ann Entomol Soc Am. 1968 Jan;61(1):116–119. doi: 10.1093/aesa/61.1.116. [DOI] [PubMed] [Google Scholar]
  17. REEVES W. C., HAMMON W. M., LONGSHORE W. A., Jr, McCLURE H. E., GEIB A. F. Epidemiology of the arthropod-borne viral encephalitides in Kern County, California, 1943-1952. Publ Public Health Univ Calif. 1962 Jun 6;4:1–257. [PubMed] [Google Scholar]
  18. STABLER R. M. Notes on certain species of mosquitoes from Delaware County, Pennsylvania. Mosq News. 1948 Mar;8(1):17–19. [PubMed] [Google Scholar]
  19. Saugstad E. S., Dalrymple J. M., Eldridge B. F. Ecology of arboviruses in a Maryland freshwater swamp. I. Population dynamics and habitat distribution of potential mosquito vectors. Am J Epidemiol. 1972 Aug;96(2):114–122. doi: 10.1093/oxfordjournals.aje.a121437. [DOI] [PubMed] [Google Scholar]
  20. Sponseller M. L., Binn L. N., Wooding W. L., Yager R. H. Field strains of western encephalitis virus in ponies: virologic, clinical, and pathologic observations. Am J Vet Res. 1966 Nov;27(121):1591–1598. [PubMed] [Google Scholar]
  21. TEMPELIS C. H., REEVES W. C., BELLAMY R. E., LOFY M. F. A THREE-YEAR STUDY OF THE FEEDING HABITS OF CULEX TARSALIS IN KERN COUNTY, CALIFORNIA. Am J Trop Med Hyg. 1965 Jan;14:170–177. doi: 10.4269/ajtmh.1965.14.170. [DOI] [PubMed] [Google Scholar]
  22. Tempelis C. H., Washino R. K. Host-feeding patterns of Culex tarsalis in the Sacramento Valley, California, with notes on other species. J Med Entomol. 1967 Aug 10;4(3):315–318. doi: 10.1093/jmedent/4.3.315. [DOI] [PubMed] [Google Scholar]
  23. Young N. A., Johnson K. M. Antigenic variants of Venezuelan equine encephalitis virus: their geographic distribution and epidemiologic significance. Am J Epidemiol. 1969 Mar;89(3):286–307. doi: 10.1093/oxfordjournals.aje.a120942. [DOI] [PubMed] [Google Scholar]

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