Abstract
Elevation of creatine kinase (CK) in serum after exertion is a reliable marker of skeletal muscle injury. Limited data exist on CK levels in conditioned athletes after endurance training and competition. Serum CK was measured by a kinetic UV method (normal < 100 U/L) in 15 long distance runners before (pre-race), 24 hours after (post-race) and four weeks following (post-race) the 1979 Boston Marathon. CK levels were elevated throughout the study. Mean values for all runners and for those finishing before and after three hours and 30 minutes are as follows: Post-race CK was significantly elevated among the ten faster as compared to the five slower runners (p = 0.025). Elevations of creatine kinase drawn 24 hours post-marathon are inversely related to finishing times among the runners tested.
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Selected References
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- Bergström J., Hermansen L., Hultman E., Saltin B. Diet, muscle glycogen and physical performance. Acta Physiol Scand. 1967 Oct-Nov;71(2):140–150. doi: 10.1111/j.1748-1716.1967.tb03720.x. [DOI] [PubMed] [Google Scholar]
- Costill D. L., Fink W. J., Pollock M. L. Muscle fiber composition and enzyme activities of elite distance runners. Med Sci Sports. 1976 Summer;8(2):96–100. [PubMed] [Google Scholar]
- Demos M. A., Gitin E. L., Kagen L. J. Exercise myoglobinemia and acute exertional rhabdomyolysis. Arch Intern Med. 1974 Oct;134(4):669–673. [PubMed] [Google Scholar]
- FOWLER W. M., Jr, CHOWDHURY S. R., PEARSON C. M., GARDNER G., BRATTON R. Changes in serum enzyme levels after exercise in trained and untrained subjects. J Appl Physiol. 1962 Nov;17:943–946. doi: 10.1152/jappl.1962.17.6.943. [DOI] [PubMed] [Google Scholar]
- Hermansen L., Hultman E., Saltin B. Muscle glycogen during prolonged severe exercise. Acta Physiol Scand. 1967 Oct-Nov;71(2):129–139. doi: 10.1111/j.1748-1716.1967.tb03719.x. [DOI] [PubMed] [Google Scholar]
- Holloszy J. O., Booth F. W. Biochemical adaptations to endurance exercise in muscle. Annu Rev Physiol. 1976;38:273–291. doi: 10.1146/annurev.ph.38.030176.001421. [DOI] [PubMed] [Google Scholar]
- King S. W., Statland B. E., Savory J. The effect of a short burst of exercise on activity values of enzymes in sera of healthy young men. Clin Chim Acta. 1976 Oct 15;72(2):211–218. doi: 10.1016/0009-8981(76)90075-9. [DOI] [PubMed] [Google Scholar]
- LaPorta M. A., Linde H. W., Bruce D. L., Fitzsimons E. J. Elevation of creatine phosphokinase in young men after recreational exercise. JAMA. 1978 Jun 23;239(25):2685–2686. doi: 10.1001/jama.239.25.2685. [DOI] [PubMed] [Google Scholar]
- Olerud J. E., Homer L. D., Carroll H. W. Serum myoglobin levels predicted from serum enzyme values. N Engl J Med. 1975 Sep 4;293(10):483–485. doi: 10.1056/NEJM197509042931006. [DOI] [PubMed] [Google Scholar]
- Riley W. J., Pyke F. S., Roberts A. D., England J. F. The effect of long-distance running on some biochemical variables. Clin Chim Acta. 1975 Nov 15;65(1):83–89. doi: 10.1016/0009-8981(75)90338-1. [DOI] [PubMed] [Google Scholar]
- Thomson W. H., Sweetin J. C., Hamilton I. J. ATP and muscle enzyme efflux after physical exertion. Clin Chim Acta. 1975 Mar 10;59(2):241–245. doi: 10.1016/0009-8981(75)90035-2. [DOI] [PubMed] [Google Scholar]