Table 2.
Results of Fermentation Experiments (Runs A-D)a
| Cyclodepsipeptide and CH2Cl2 Fraction | A (mg) | B (mg) | C (mg) | D (mg) |
|---|---|---|---|---|
| CH2Cl2 Fractionb | 60.0 | 92.0 | 185.0 | 140.0 |
| Cyclodepsipeptide 1 | 7.0 | 5.3 | 3.7 | 9.0 |
| Cyclodepsipeptide 2 | 1.7 | 2.0 | 0.9 | 2.3 |
Run A: culture media with addition of DL-serine. Run B: culture media with addition of 2-hydroxyvaleric acid. Run C: culture media with addition of DL-tyrosine. Run D: culture media with addition of shikimic acid.
CH2Cl2 extract fraction (from each 380-L fermentation) obtained from the CH2Cl2/CH3CHOH-H2O (3:2) solvent partition isolation step.