Table 3.
Inhibition of the Murine P388 Lymphocytic Leukemia (ED50 μg/mL) and Human Cancer Cell Line (GI50 μg/mL) by Cyclodepsipeptides 1, 2 and 3.
| Cyclodepsipeptides | P388 Murine leukemia | BXPC-3 Pancreas | MCF-7 Breast | SF268 CNS | NCI-H460 Lung | KM20L2 Colon | DU-145 Prostate |
|---|---|---|---|---|---|---|---|
| 1 | 0.0037 | 0.47 | 0.0006 | 0.0016 | 0.0006 | 0.0006 | 0.00018 |
| 2 | 0.033 | 1.2 | 0.00064 | 0.016 | 0.00063 | 0.00058 | <0.0001 |
| 3 | 0.045 | 0.0066 | 0.004 | 0.0035 | <0.001 | 0.0024 | 0.0026 |