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. Author manuscript; available in PMC: 2009 Oct 15.
Published in final edited form as: Neuroscience. 2008 Aug 9;156(3):788–799. doi: 10.1016/j.neuroscience.2008.07.063

Fig. 6.

Fig. 6

Measurement of the 5.4 kDa C-terminal proTRH-derived peptide and TRH in the arcuate nucleus/median eminence. Rats were implanted with placebo or morphine pellets for 24 h or seven days. The amount in pg of TRH and the 5.4 kDa C-terminal proTRH-derived peptide was determined by specific RIA, the ratio of the two was calculated for each animal (n=3-4) and the ratios were averaged. **p<0.001. P, placebo; M, morphine.