Table 1.

Pre-prandial measurements (at the time of the feeding study) in baboons with a closed, small and moderate PDA

	Closed (Qp/Qs ≤1.2)	Small Shunt (Qp/Qs ≥1.4 and <2)	Moderate Shunt (Qp/Qs >2)
Number of animals	13	13	11
Number of studies	31	20	21
Postnatal age (d)	11.5 ± 1.1	11.6 ± 1.0	11.6 ± 1.3
Weight (gm)	365 ± 47	374 ± 40	382 ± 49
Qp/Qs	1.00 ± 0.07	1.65 ± 0.18*	2.26 ± 0.40*
LVEDD (mm)	0.9 ± 0.1	1.0 ± 0.1*	1.1 ± 0.1*
Effective systemic output (ml/kg/min)	228 ± 45	254 ± 57	192 ± 43*
BP systolic (mm Hg)	65 ± 8	56 ± 7*	56 ± 8*
BP diastolic (mm Hg)	34 ± 7	30 ± 7	31 ± 7
BP mean (mm Hg)	46 ± 5	41 ± 5*	42 ± 6*
HR (beats/min)	151 ± 15	158 ± 12*	162 ± 13*
Feeding (ml/kg/feed)	4.2 ± 1.0	3.8 ± 0.8	3.9 ± 0.9
PaO2 (mm Hg)	71.9 ± 4.7	69.9 ± 0.6	71.4 ± 3.5
PaCO2 (mm Hg)	51.4 ± 0.9	50.3 ± 0.2	52.1 ± 1.5
pH	7.34 ± 0.1	7.35 ± 0.1	7.33 ± 0.1
Hematocrit (%)	37±3	38±2	36±3
VI	36.7 ± 3.3	38.9 ± 0.6	40.0 ± 4.9
OI	5.3 ± 0.6	5.3 ± 0.1	4.5 ± 0.5

Values are means ± SD.

^*p<0.05 versus closed ductus group