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Cytotoxicity (A) and apoptosis (B) in DU145 cells following treatment with 177Lu-hu3S193 following 120 hrs incubation as indicated. Percentage survival was calculated using the formula [(A490treated/A490untreated control) × 100] (mean ± SD, n = 6). Apoptosis was determined by an ELISA assessing histone associated DNA fragmentation, and relative apoptosis determined using the formula (Apoptosistreated/Apoptosisuntreated control) (mean ± SD, n = 3).
