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. 1988 Dec;56(12):3326–3328. doi: 10.1128/iai.56.12.3326-3328.1988

Plasmodium chabaudi malaria: protective immunization with surface membranes of infected erythrocytes.

F Wunderlich 1, H H Brenner 1, M Helwig 1
PMCID: PMC259746  PMID: 3182084

Abstract

Plasmodium chabaudi-susceptible NMRI and B10.A mice were vaccinated with host cell plasma membranes isolated from P. chabaudi-infected erythrocytes. Most of the mice were protected from the lethal consequences of challenge with the homologous parasite, although protection was unassociated with a reduction in the course or peak of parasitemia. Vaccination also induced the production of antibodies against Pc90, which is the immunodominant protein expressed by parasites in host cell plasma membranes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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