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. 1987 Nov;55(11):2850–2853. doi: 10.1128/iai.55.11.2850-2853.1987

Characterization of a native polysaccharide hapten from Brucella melitensis.

E Moreno 1, H Mayer 1, I Moriyon 1
PMCID: PMC259989  PMID: 3117696

Abstract

The 13C nuclear magnetic resonance spectrum of Brucella melitensis native polysaccharide hapten proved to be very similar to that generated by the O-specific chain (PS) isolated from B. melitensis lipopolysaccharide; that is, to a linear polymer in which the repeating unit is composed of five N-formylperosaminyl residues, one of them being substituted at position C-3 and the other four at position C-2. The serological analysis suggests that the so-called A determinant is present solely in Brucella abortus PS, the M determinant is only in B. melitensis PS, and the extensive cross-reaction observed is due to a determinant shared by both polysaccharides.

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Selected References

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