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. 1986 Dec;54(3):909–912. doi: 10.1128/iai.54.3.909-912.1986

Effect of T-lymphocyte suppression on the parasite burden in Leishmania major-infected, genetically susceptible BALB/c mice.

W Solbach, K Forberg, M Röllinghoff
PMCID: PMC260260  PMID: 3491051

Abstract

Treatment of Leishmania major-infected, genetically susceptible BALB/c mice with the T-lymphocyte-immunosuppressive drug cyclosporin A (CyA) resulted in a significantly reduced parasite burden in the local site of infection and in the draining lymph nodes. These data indicate that T cells are pivotal for the propagation of L. major in vivo.

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Selected References

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