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. 1987 Jan;55(1):227–232. doi: 10.1128/iai.55.1.227-232.1987

Isolation of Coccidioides immitis F antigen by immunoaffinity chromatography with monospecific antiserum.

R A Cox, L A Britt, R A Michael
PMCID: PMC260307  PMID: 3098685

Abstract

Detection of antibody to Coccidioides immitis F antigen is of proved value in the diagnosis of coccidioidomycosis. This antibody is demonstrable by use of an immunodiffusion assay with reference coccidioidin antigen and antiserum to C. immitis. Using a combination of lectin affinity and immunoaffinity chromatography, we isolated the F antigen from coccidioidin and prepared monospecific antibody to the purified antigen. The availability of these reagents will enable the development of a sensitive and specific assay for detecting serologic reactivity to this antigen.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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