Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1987 Jan;55(1):266–268. doi: 10.1128/iai.55.1.266-268.1987

Immunological study of cross-reactive polysaccharide antigens (types a, d, and h) of oral Streptococcus spp. with monoclonal antibodies.

F Ota, H Kato, K Fukui
PMCID: PMC260314  PMID: 2432015

Abstract

Two monoclonal antibodies against the cross-reactive antigens of S. cricetus (type a) and S. sobrinus (type d) were isolated. Galactose and especially melibiose inhibited the precipitin reaction markedly. Inhibition by melibiose was over 200-fold stronger than that by galactose. This may indicate that galactose-alpha 1, 6-glucose is the predominant antigenic determinant of this cross-reactive antigen. This antigen was also found in S. sobrinus type h strains, but no antigen was found in one type d strain (OMZ176).

Full text

PDF
266

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beighton D., Russell R. R., Hayday H. The isolation of characterization of Streptococcus mutans serotype h from dental plaque of monkeys (Macaca fascicularis). J Gen Microbiol. 1981 Jun;124(2):271–279. doi: 10.1099/00221287-124-2-271. [DOI] [PubMed] [Google Scholar]
  2. Brown T. A., Bleiweis A. S. Chemical, immunochemical, and structural studies of the cross-reactive antigens of Streptococcus mutans AHT and B13. Infect Immun. 1979 May;24(2):326–336. doi: 10.1128/iai.24.2.326-336.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. FITZGERALD R. J., KEYES P. H. Demonstration of the etiologic role of streptococci in experimental caries in the hamster. J Am Dent Assoc. 1960 Jul;61:9–19. doi: 10.14219/jada.archive.1960.0138. [DOI] [PubMed] [Google Scholar]
  4. Galfre G., Howe S. C., Milstein C., Butcher G. W., Howard J. C. Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature. 1977 Apr 7;266(5602):550–552. doi: 10.1038/266550a0. [DOI] [PubMed] [Google Scholar]
  5. Gibbons R. J., Houte J. V. Bacterial adherence in oral microbial ecology. Annu Rev Microbiol. 1975;29:19–44. doi: 10.1146/annurev.mi.29.100175.000315. [DOI] [PubMed] [Google Scholar]
  6. Hamada S., Slade H. D. Biology, immunology, and cariogenicity of Streptococcus mutans. Microbiol Rev. 1980 Jun;44(2):331–384. doi: 10.1128/mr.44.2.331-384.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Kato H., Ota F., Fukui K., Yagawa K. Monoclonal antibody to Streptococcus mutans type e cell wall polysaccharide antigen. Infect Immun. 1986 May;52(2):628–630. doi: 10.1128/iai.52.2.628-630.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Linzer R., Slade H. D. Purification and characterization of Streptococcus mutans group d cell wall polysaccharide antigen. Infect Immun. 1974 Aug;10(2):361–368. doi: 10.1128/iai.10.2.361-368.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Mukasa H., Slade H. D. Extraction, purification, and chemical and immunological properties of the Streptococcus mutans group "a" polysaccharide cell wall antigen. Infect Immun. 1973 Aug;8(2):190–198. doi: 10.1128/iai.8.2.190-198.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Okahashi N., Nishida Y., Koga T., Hamada S. Immunochemical characteristics of Streptococcus mutans serotype h carbohydrate antigen. Microbiol Immunol. 1984;28(4):407–413. doi: 10.1111/j.1348-0421.1984.tb00692.x. [DOI] [PubMed] [Google Scholar]
  11. Ota F., Kiso M., Okada K., Kato H., Hirota K., Fukui K., Yasuoka M., Ono M., Uegaki K., Morimoto Y. Streptococcus mutans serotype b strain (St. rattus, Coykendall): first isolation in Japan from human dental plaque. Microbiol Immunol. 1985;29(10):1005–1010. doi: 10.1111/j.1348-0421.1985.tb02964.x. [DOI] [PubMed] [Google Scholar]
  12. Prakobphol A., Linzer R., Genco R. J. Purification and characterization of a rhamnose-containing cell wall antigen of Streptococcus mutans B13 (serotype d). Infect Immun. 1980 Jan;27(1):150–157. doi: 10.1128/iai.27.1.150-157.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Scherp H. W. Dental caries: prospects for prevention. Science. 1971 Sep 24;173(4003):1199–1205. doi: 10.1126/science.173.4003.1199. [DOI] [PubMed] [Google Scholar]
  14. Takada K., Wyszomirska J., Shiota T. Serological characterization of Streptococcus mutans serotype polysaccharide g and its different molecular weight forms. Infect Immun. 1984 Aug;45(2):464–469. doi: 10.1128/iai.45.2.464-469.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Van de Rijn I., Bleiweis A. S. Antigens of Streptococcus mutans. I. Characterization of a serotype-specific determinant from Streptococcus mutans. Infect Immun. 1973 May;7(5):795–804. doi: 10.1128/iai.7.5.795-804.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES