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. 1987 Jan;55(1):273–276. doi: 10.1128/iai.55.1.273-276.1987

Characterization of protein I from serum-sensitive and serum-resistant transformants of Neisseria gonorrhoeae.

R C Judd, M Tam, K Joiner
PMCID: PMC260316  PMID: 3098687

Abstract

The protein IAs of serum-sensitive (FA635) and serum-resistant (FA638) transformants of Neisseria gonorrhoeae, which have identical pedigrees, have been shown to be different by the use of a monoclonal antibody and were also shown to be different by proteinase K cleavage and primary structural and surface peptide mapping. The difference in structure is within the surface-exposed region of the molecule. The only other difference observed between the two strains was a very slight difference in lipooligosaccharide silver staining in sodium dodecyl sulfate-polyacrylamide gel electrophoresis. These data suggest that protein I alone or in combination with lipooligosaccharide may significantly contribute to serum resistance.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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