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. 1987 Jun;55(6):1533–1535. doi: 10.1128/iai.55.6.1533-1535.1987

Cytotoxicity of Shiga toxin for primary cultures of human colonic and ileal epithelial cells.

M P Moyer, P S Dixon, S W Rothman, J E Brown
PMCID: PMC260549  PMID: 3570477

Abstract

Shiga toxin purified from Shigella dysenteriae 1 was cytotoxic to cultured epithelial cells from human colon and ileum. The cytotoxicity, which affected only about 50% of treated cells, was neutralized by rabbit antiserum monospecific for Shiga toxin and mediated by protein synthesis inhibition.

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Selected References

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