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. 1987 Sep;55(9):2314–2316. doi: 10.1128/iai.55.9.2314-2316.1987

Transposon mutagenesis of group B streptococcus beta-hemolysin biosynthesis.

J N Weiser, C E Rubens
PMCID: PMC260700  PMID: 3040595

Abstract

Beta-hemolysin production by group B streptococci (GBS) is speculated to be a major virulence factor of the organism. A virulent, beta-hemolytic group B streptococcus strain was mutagenized with the self-conjugative transposon Tn916 to derive isogenic strains with mutations only in the gene(s) responsible for beta-hemolysin biosynthesis. There was no significant difference between the virulence of the parent strain and that of the mutant strains in a neonatal rat sepsis model.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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