Abstract
Multiple primary cancers in a single individual are rare when more than three distinct lesions are considered. This article reports a patient who developed four separate primary cancers: squamous cell carcinoma of the larynx, squamous carcinoma of the lung, adenocarcinoma of the breast, and adenocarcinoma of the colon. No specific hereditary syndrome could be identified from this patient's pedigree. Individuals with a history of multiple cancers should have a complete family history evaluation and follow-up for development of subsequent primaries.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Berg J. W., Hajdu S. I., Foote F. W., Jr The prevalence of latent cancers in cancer patients. Arch Pathol. 1971 Feb;91(2):183–186. [PubMed] [Google Scholar]
- Hajdu S. I., Hajdu E. O. Multiple primary malignant tumors. J Am Geriatr Soc. 1968 Jan;16(1):16–26. doi: 10.1111/j.1532-5415.1968.tb03965.x. [DOI] [PubMed] [Google Scholar]
- Lynch H. T., Kimberling W., Albano W. A., Lynch J. F., Biscone K., Schuelke G. S., Sandberg A. A., Lipkin M., Deschner E. E., Mikol Y. B. Hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II). I. Clinical description of resource. Cancer. 1985 Aug 15;56(4):934–938. doi: 10.1002/1097-0142(19850815)56:4<934::aid-cncr2820560439>3.0.co;2-i. [DOI] [PubMed] [Google Scholar]
- Ostrowski M. J. Five separate malignancies in one patient all apparently successfully treated. Br Med J. 1975 Dec 27;4(5999):736–737. doi: 10.1136/bmj.4.5999.736. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swaroop V. S., Winawer S. J., Lightdale C. J., Lipkin M. Six primary cancers in individuals. Report of four cases. Cancer. 1988 Mar 15;61(6):1253–1254. doi: 10.1002/1097-0142(19880315)61:6<1253::aid-cncr2820610633>3.0.co;2-g. [DOI] [PubMed] [Google Scholar]