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Journal of the National Medical Association logoLink to Journal of the National Medical Association
. 1994 Dec;86(12):926–929.

Evaluation of massive volume replacement in the penetrating trauma patient.

K J Mitchell 1, K E Moncure 1, C Onyeije 1, M S Rao 1, S Siram 1
PMCID: PMC2607697  PMID: 7861471

Abstract

The records of 163 penetrating trauma patients who required surgery in a 36-month period between 1988 and 1990 were reviewed. Those patients with head trauma were excluded. Thirty patients were identified as having: similar Injury Severity Scores (ISS), received at least 8 L of crystalloid, and received at least 4 units of packed red blood cells during the first 24 hours after admission. There were 22 (73%) survivors and 8 (27%) nonsurvivors. Charts were reviewed for a variety of variables to determine which characteristics distinguished nonsurvivors from survivors. The mean ISS was 30.5 +/- 5.5. As a group, nonsurvivors received more blood transfusions (14.9 +/- 4.9 versus 5.0 +/- 1.14), had longer durations of shock (55.6 +/- 18 minutes versus 19.3 +/- 11.7 minutes), and had lower core body temperatures (92.6 degrees F +/- 2.2 versus 95.1 degrees F +/- 2.4) than survivors. Nonsurvivors also had lower hemoglobin levels (7.84 +/- 1 versus 9.1 +/- 2.3) and platelet counts (134.2 +/- 14.1 versus 188.6 +/- 6.3) than survivors. In addition, nonsurvivors demonstrated greater incidence of three major risk factors than did the survivors: hypothermia (75% versus 41%), acidosis (100% versus 27%), and coagulopathy (62% versus 4.5%). Therapeutic measures to limit these risk factors for increased mortality may maximize the chance of survival in these patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baker S. P., O'Neill B., Haddon W., Jr, Long W. B. The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 1974 Mar;14(3):187–196. [PubMed] [Google Scholar]
  2. Ferrara A., MacArthur J. D., Wright H. K., Modlin I. M., McMillen M. A. Hypothermia and acidosis worsen coagulopathy in the patient requiring massive transfusion. Am J Surg. 1990 Nov;160(5):515–518. doi: 10.1016/s0002-9610(05)81018-9. [DOI] [PubMed] [Google Scholar]
  3. Luna G. K., Maier R. V., Pavlin E. G., Anardi D., Copass M. K., Oreskovich M. R. Incidence and effect of hypothermia in seriously injured patients. J Trauma. 1987 Sep;27(9):1014–1018. doi: 10.1097/00005373-198709000-00010. [DOI] [PubMed] [Google Scholar]
  4. Satiani B., Fried S. J., Zeeb P., Falcone R. E. Normothermic rapid volume replacement in traumatic hypovolemia. A prospective analysis using a new device. Arch Surg. 1987 Sep;122(9):1044–1047. doi: 10.1001/archsurg.1987.01400210082012. [DOI] [PubMed] [Google Scholar]
  5. Wudel J. H., Morris J. A., Jr, Yates K., Wilson A., Bass S. M. Massive transfusion: outcome in blunt trauma patients. J Trauma. 1991 Jan;31(1):1–7. [PubMed] [Google Scholar]

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