Abstract
The records of 163 penetrating trauma patients who required surgery in a 36-month period between 1988 and 1990 were reviewed. Those patients with head trauma were excluded. Thirty patients were identified as having: similar Injury Severity Scores (ISS), received at least 8 L of crystalloid, and received at least 4 units of packed red blood cells during the first 24 hours after admission. There were 22 (73%) survivors and 8 (27%) nonsurvivors. Charts were reviewed for a variety of variables to determine which characteristics distinguished nonsurvivors from survivors. The mean ISS was 30.5 +/- 5.5. As a group, nonsurvivors received more blood transfusions (14.9 +/- 4.9 versus 5.0 +/- 1.14), had longer durations of shock (55.6 +/- 18 minutes versus 19.3 +/- 11.7 minutes), and had lower core body temperatures (92.6 degrees F +/- 2.2 versus 95.1 degrees F +/- 2.4) than survivors. Nonsurvivors also had lower hemoglobin levels (7.84 +/- 1 versus 9.1 +/- 2.3) and platelet counts (134.2 +/- 14.1 versus 188.6 +/- 6.3) than survivors. In addition, nonsurvivors demonstrated greater incidence of three major risk factors than did the survivors: hypothermia (75% versus 41%), acidosis (100% versus 27%), and coagulopathy (62% versus 4.5%). Therapeutic measures to limit these risk factors for increased mortality may maximize the chance of survival in these patients.
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Selected References
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- Baker S. P., O'Neill B., Haddon W., Jr, Long W. B. The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 1974 Mar;14(3):187–196. [PubMed] [Google Scholar]
- Ferrara A., MacArthur J. D., Wright H. K., Modlin I. M., McMillen M. A. Hypothermia and acidosis worsen coagulopathy in the patient requiring massive transfusion. Am J Surg. 1990 Nov;160(5):515–518. doi: 10.1016/s0002-9610(05)81018-9. [DOI] [PubMed] [Google Scholar]
- Luna G. K., Maier R. V., Pavlin E. G., Anardi D., Copass M. K., Oreskovich M. R. Incidence and effect of hypothermia in seriously injured patients. J Trauma. 1987 Sep;27(9):1014–1018. doi: 10.1097/00005373-198709000-00010. [DOI] [PubMed] [Google Scholar]
- Satiani B., Fried S. J., Zeeb P., Falcone R. E. Normothermic rapid volume replacement in traumatic hypovolemia. A prospective analysis using a new device. Arch Surg. 1987 Sep;122(9):1044–1047. doi: 10.1001/archsurg.1987.01400210082012. [DOI] [PubMed] [Google Scholar]
- Wudel J. H., Morris J. A., Jr, Yates K., Wilson A., Bass S. M. Massive transfusion: outcome in blunt trauma patients. J Trauma. 1991 Jan;31(1):1–7. [PubMed] [Google Scholar]