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. 1997 Jun;89(6):392–396.

Profile of dementia in a Nigerian community--types, pattern of impairment, and severity rating.

A Ogunniyi 1, O Gureje 1, O Baiyewu 1, F Unverzagt 1, K S Hall 1, S Oluwole 1, B O Osuntokun 1, H C Hendrie 1
PMCID: PMC2608156  PMID: 9195799

Abstract

Out of 2494 subjects screened in a Nigerian community, 28 patients with dementia were identified. Alzheimer's disease was diagnosed in 18 patients (64.3%), 16 of whom had probable Alzheimer's disease. Eight patients (28.6%) had vascular dementia while one patient each had parkinsonism with dementia and depression with dementia. Patients with Alzheimer's disease were significantly older, predominantly females and illiterates. Cognitive deficit commonly took the form of memory and judgment impairment while financial mismanagement was the most frequent impaired activity of daily living. More than half of the cases had mild disease on severity rating and were comprised mainly of Alzheimer's disease subjects. These results confirm the higher frequency of Alzheimer's disease over the other types as reported in other communities.

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Selected References

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  1. Baldereschi M., Amato M. P., Nencini P., Pracucci G., Lippi A., Amaducci L., Gauthier S., Beatty L., Quiroga P., Klassen G. Cross-national interrater agreement on the clinical diagnostic criteria for dementia. WHO-PRA Age-Associated Dementia Working Group, WHO-Program for Research on Aging, Health of Elderly Program. Neurology. 1994 Feb;44(2):239–242. doi: 10.1212/wnl.44.2.239. [DOI] [PubMed] [Google Scholar]
  2. Callahan C. M., Hall K. S., Hui S. L., Musick B. S., Unverzagt F. W., Hendrie H. C. Relationship of age, education, and occupation with dementia among a community-based sample of African Americans. Arch Neurol. 1996 Feb;53(2):134–140. doi: 10.1001/archneur.1996.00550020038013. [DOI] [PubMed] [Google Scholar]
  3. Fratiglioni L., Grut M., Forsell Y., Viitanen M., Grafström M., Holmén K., Ericsson K., Bäckman L., Ahlbom A., Winblad B. Prevalence of Alzheimer's disease and other dementias in an elderly urban population: relationship with age, sex, and education. Neurology. 1991 Dec;41(12):1886–1892. doi: 10.1212/wnl.41.12.1886. [DOI] [PubMed] [Google Scholar]
  4. Hendrie H. C., Osuntokun B. O., Hall K. S., Ogunniyi A. O., Hui S. L., Unverzagt F. W., Gureje O., Rodenberg C. A., Baiyewu O., Musick B. S. Prevalence of Alzheimer's disease and dementia in two communities: Nigerian Africans and African Americans. Am J Psychiatry. 1995 Oct;152(10):1485–1492. doi: 10.1176/ajp.152.10.1485. [DOI] [PubMed] [Google Scholar]
  5. Heyman A., Fillenbaum G., Prosnitz B., Raiford K., Burchett B., Clark C. Estimated prevalence of dementia among elderly black and white community residents. Arch Neurol. 1991 Jun;48(6):594–598. doi: 10.1001/archneur.1991.00530180046016. [DOI] [PubMed] [Google Scholar]
  6. Hughes C. P., Berg L., Danziger W. L., Coben L. A., Martin R. L. A new clinical scale for the staging of dementia. Br J Psychiatry. 1982 Jun;140:566–572. doi: 10.1192/bjp.140.6.566. [DOI] [PubMed] [Google Scholar]
  7. Katzman R. Alzheimer's disease. N Engl J Med. 1986 Apr 10;314(15):964–973. doi: 10.1056/NEJM198604103141506. [DOI] [PubMed] [Google Scholar]
  8. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E. M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984 Jul;34(7):939–944. doi: 10.1212/wnl.34.7.939. [DOI] [PubMed] [Google Scholar]
  9. Morris J. C., Heyman A., Mohs R. C., Hughes J. P., van Belle G., Fillenbaum G., Mellits E. D., Clark C. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology. 1989 Sep;39(9):1159–1165. doi: 10.1212/wnl.39.9.1159. [DOI] [PubMed] [Google Scholar]
  10. Ogunniyi A. O., Osuntokun B. O., Lekwauwa U. B., Falope Z. F. Rarity of dementia (by DSM-III-R) in an urban community in Nigeria. East Afr Med J. 1992 Feb;69(2):64–68. [PubMed] [Google Scholar]
  11. Ogunniyi A., Lekwauwa U. G., Falope Z. F., Osuntokun B. O. Clinically-diagnosed dementing illnesses in Ibadan: features, types and associated conditions. Afr J Med Med Sci. 1993 Sep;22(3):61–64. [PubMed] [Google Scholar]
  12. Osuntokun B. O., Adeuja A. O., Schoenberg B. S., Bademosi O., Nottidge V. A., Olumide A. O., Ige O., Yaria F., Bolis C. L. Neurological disorders in Nigerian Africans: a community-based study. Acta Neurol Scand. 1987 Jan;75(1):13–21. doi: 10.1111/j.1600-0404.1987.tb07883.x. [DOI] [PubMed] [Google Scholar]
  13. Osuntokun B. O., Ogunniyi A., Akang E. E., Aghadiuno P. U., Ilori A., Bamgboye E. A., Beyreuther K., Masters C. Beta A4-amyloid in the brains of non-demented Nigerian Africans. Lancet. 1994 Jan 1;343(8888):56–56. doi: 10.1016/s0140-6736(94)90910-5. [DOI] [PubMed] [Google Scholar]
  14. Sacco R. L. Risk factors and outcomes for ischemic stroke. Neurology. 1995 Feb;45(2 Suppl 1):S10–S14. [PubMed] [Google Scholar]
  15. Schoenberg B. S., Anderson D. W., Haerer A. F. Severe dementia. Prevalence and clinical features in a biracial US population. Arch Neurol. 1985 Aug;42(8):740–743. doi: 10.1001/archneur.1985.04210090004002. [DOI] [PubMed] [Google Scholar]
  16. Tekle-Haimanot R., Abebe M., Gebre-Mariam A., Forsgren L., Heijbel J., Holmgren G., Ekstedt J. Community-based study of neurological disorders in rural central Ethiopia. Neuroepidemiology. 1990;9(5):263–277. doi: 10.1159/000110783. [DOI] [PubMed] [Google Scholar]

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