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Journal of the National Medical Association logoLink to Journal of the National Medical Association
. 1996 Nov;88(11):714–716.

Extrapulmonary sarcoidosis: rapid spontaneous remission of marked splenomegaly.

Y Ali 1, N A Popescu 1, T J Woodlock 1
PMCID: PMC2608170  PMID: 8961690

Abstract

Splenomegaly, when present as a manifestation of sarcoidosis, may cause pressure symptoms and hypersplenism. Literature reports of giant splenomegaly are few in number and describe the use of aggressive intervention with systemic steroids and splenectomy. However, the natural history of splenic sarcoidosis is not well-defined, particularly the potential for spontaneous remission as seen in pulmonary sarcoidosis. In the case described here, a spontaneous remission of giant splenomegaly from sarcoidosis was observed. Careful follow-up appears to be appropriate management for at least some of these patients.

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Selected References

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