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. 1984 Dec;46(3):835–838. doi: 10.1128/iai.46.3.835-838.1984

Association of hydroxamate siderophore (aerobactin) with Escherichia coli isolated from patients with bacteremia.

J Z Montgomerie, A Bindereif, J B Neilands, G M Kalmanson, L B Guze
PMCID: PMC261622  PMID: 6389366

Abstract

Clinical isolates of Escherichia coli were examined for the presence of hydroxamate siderophore (aerobactin). The incidence of aerobactin-positive strains of E. coli from the blood was greater than the incidence of these strains isolated from other sites. The presence of aerobactin and the virulence of strains of E. coli in urinary tract infection were also examined in mice. The presence of aerobactin in the strains of E. coli correlated with virulence as measured by proportion of deaths but not with renal infection. These results suggest that the presence of aerobactin may be a significant factor in the invasion of the blood stream.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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