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Journal of Nematology logoLink to Journal of Nematology
. 1997 Sep;29(3):250–254.

DNA Sequences from Formalin-Fixed Nematodes: Integrating Molecular and Morphological Approaches to Taxonomy

W Kelley Thomas, J T Vida, Linda M Frisse, Manuel Mundo, James G Baldwin
PMCID: PMC2619797  PMID: 19274156

Abstract

To effectively integrate DNA sequence analysis and classical nematode taxonomy, we must be able to obtain DNA sequences from formalin-fixed specimens. Microdissected sections of nematodes were removed from specimens fixed in formalin, using standard protocols and without destroying morphological features. The fixed sections provided sufficient template for multiple polymerase chain reaction-based DNA sequence analyses.

Keywords: DNA sequence, formalin, microdissection, molecular biology, nematode, polymerase chain reaction, taxonomy

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