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. 1986 Apr;52(1):341–343. doi: 10.1128/iai.52.1.341-343.1986

Release of interleukin-1 by peripheral blood mononuclear cells in patients with tuberculosis and active inflammation.

S W Chensue, M P Davey, D G Remick, S L Kunkel
PMCID: PMC262243  PMID: 3485575

Abstract

Peripheral blood monocytes from patients with active tuberculosis and acute inflammatory disease showed spontaneous interleukin-1 production when compared with those from control patients or healthy controls. Moreover, interleukin-1 production appeared to be a more specific indicator of active disease than were other commonly used indices, such as the erythrocyte sedimentation rate and serum C-reactive protein levels.

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Selected References

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  1. Alcocer-Varela J., Martinez-Cordero E., Alarcon-Segovia D. Spontaneous production of, and defective response to, interleukin-1 by peripheral blood mononuclear cells from patients with scleroderma. Clin Exp Immunol. 1985 Mar;59(3):666–672. [PMC free article] [PubMed] [Google Scholar]
  2. Dinarello C. A., Wolff S. M. Molecular basis of fever in humans. Am J Med. 1982 May;72(5):799–819. doi: 10.1016/0002-9343(82)90548-4. [DOI] [PubMed] [Google Scholar]
  3. Gillis S., Ferm M. M., Ou W., Smith K. A. T cell growth factor: parameters of production and a quantitative microassay for activity. J Immunol. 1978 Jun;120(6):2027–2032. [PubMed] [Google Scholar]
  4. Hind C. R., Winearls C. G., Pepys M. B. Correlation of disease activity in systemic vasculitis with serum C-reactive protein measurement. A prospective study of thirty-eight patients. Eur J Clin Invest. 1985 Apr;15(2):89–94. doi: 10.1111/j.1365-2362.1985.tb00150.x. [DOI] [PubMed] [Google Scholar]
  5. Hunninghake G. W. Release of interleukin-1 by alveolar macrophages of patients with active pulmonary sarcoidosis. Am Rev Respir Dis. 1984 Apr;129(4):569–572. [PubMed] [Google Scholar]
  6. Kenny R. A., Saunders A. P., Coll A., Harrington M. G., Caspi D., Hodkinson H. M., Pepys M. B. A comparison of the erythrocyte sedimentation rate and serum C-reactive protein concentration in elderly patients. Age Ageing. 1985 Jan;14(1):15–20. doi: 10.1093/ageing/14.1.15. [DOI] [PubMed] [Google Scholar]
  7. Mizel S. B., Oppenheim J. J., Rosenstreich D. L. Characterization of lymphocyte-activating factor (LAF) produced by the macrophage cell line, P388D1. I. Enhancement of LAF production by activated T lymphocytes. J Immunol. 1978 May;120(5):1497–1503. [PubMed] [Google Scholar]
  8. Ritchie R. F., Alper C. A., Graves J., Pearson N., Larson C. Automated quantitation of proteins in serum and other biologic fluids. Am J Clin Pathol. 1973 Feb;59(2):151–159. doi: 10.1093/ajcp/59.2.151. [DOI] [PubMed] [Google Scholar]
  9. Sztein M. B., Vogel S. N., Sipe J. D., Murphy P. A., Mizel S. B., Oppenheim J. J., Rosenstreich D. L. The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen. Cell Immunol. 1981 Sep 1;63(1):164–176. doi: 10.1016/0008-8749(81)90037-x. [DOI] [PubMed] [Google Scholar]
  10. Watson S., Bullock W., Nelson K., Schauf V., Gelber R., Jacobson R. Interleukin 1 production by peripheral blood mononuclear cells from leprosy patients. Infect Immun. 1984 Sep;45(3):787–789. doi: 10.1128/iai.45.3.787-789.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]

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