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. 1996 Jul-Sep;2(3):225–230. doi: 10.3201/eid0203.960311

Legionella-like amebal pathogens--phylogenetic status and possible role in respiratory disease.

A Adeleke 1, J Pruckler 1, R Benson 1, T Rowbotham 1, M Halablab 1, B Fields 1
PMCID: PMC2626797  PMID: 8903235

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Selected References

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  1. Altschul S. F., Gish W., Miller W., Myers E. W., Lipman D. J. Basic local alignment search tool. J Mol Biol. 1990 Oct 5;215(3):403–410. doi: 10.1016/S0022-2836(05)80360-2. [DOI] [PubMed] [Google Scholar]
  2. Brown S. L., Bibb W. F., McKinney R. M. Retrospective examination of lung tissue specimens for the presence of Legionella organisms: comparison of an indirect fluorescent-antibody system with direct fluorescent-antibody testing. J Clin Microbiol. 1984 Apr;19(4):468–472. doi: 10.1128/jcm.19.4.468-472.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Chandler F. W., Hicklin M. D., Blackmon J. A. Demonstration of the agent of Legionnaires' disease in tissue. N Engl J Med. 1977 Dec 1;297(22):1218–1220. doi: 10.1056/NEJM197712012972206. [DOI] [PubMed] [Google Scholar]
  4. Cianciotto N. P., Fields B. S. Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5188–5191. doi: 10.1073/pnas.89.11.5188. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Cirillo J. D., Falkow S., Tompkins L. S. Growth of Legionella pneumophila in Acanthamoeba castellanii enhances invasion. Infect Immun. 1994 Aug;62(8):3254–3261. doi: 10.1128/iai.62.8.3254-3261.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. DROZANSKI W. Fatal bacterial infection in soil amoebae. Acta Microbiol Pol. 1956;5(3-4):315–317. [PubMed] [Google Scholar]
  7. Doebbeling B. N., Bale M. J., Koontz F. P., Helms C. M., Wenzel R. P., Pfaller M. A. Prospective evaluation of the Gen-Probe assay for detection of legionellae in respiratory specimens. Eur J Clin Microbiol Infect Dis. 1988 Dec;7(6):748–752. doi: 10.1007/BF01975041. [DOI] [PubMed] [Google Scholar]
  8. Drozanski W., Chmielewski T. Electron microscopic studies of Acanthamoeba castellanii infected with obligate intracellular bacterial parasite. Acta Microbiol Pol. 1979;28(2):123–133. [PubMed] [Google Scholar]
  9. Edelstein P. H., Bryan R. N., Enns R. K., Kohne D. E., Kacian D. L. Retrospective study of Gen-Probe rapid diagnostic system for detection of legionellae in frozen clinical respiratory tract samples. J Clin Microbiol. 1987 Jun;25(6):1022–1026. doi: 10.1128/jcm.25.6.1022-1026.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Fass R. J. Aetiology and treatment of community-acquired pneumonia in adults: an historical perspective. J Antimicrob Chemother. 1993 Jul;32 (Suppl A):17–27. doi: 10.1093/jac/32.suppl_a.17. [DOI] [PubMed] [Google Scholar]
  11. Fields B. S., Barbaree J. M., Shotts E. B., Jr, Feeley J. C., Morrill W. E., Sanden G. N., Dykstra M. J. Comparison of guinea pig and protozoan models for determining virulence of Legionella species. Infect Immun. 1986 Sep;53(3):553–559. doi: 10.1128/iai.53.3.553-559.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Fox G. E., Wisotzkey J. D., Jurtshuk P., Jr How close is close: 16S rRNA sequence identity may not be sufficient to guarantee species identity. Int J Syst Bacteriol. 1992 Jan;42(1):166–170. doi: 10.1099/00207713-42-1-166. [DOI] [PubMed] [Google Scholar]
  13. Fry N. K., Rowbotham T. J., Saunders N. A., Embley T. M. Direct amplification and sequencing of the 16S ribosomal DNA of an intracellular Legionella species recovered by amoebal enrichment from the sputum of a patient with pneumonia. FEMS Microbiol Lett. 1991 Oct 1;67(2):165–168. doi: 10.1016/0378-1097(91)90348-e. [DOI] [PubMed] [Google Scholar]
  14. Garibaldi R. A. Epidemiology of community-acquired respiratory tract infections in adults. Incidence, etiology, and impact. Am J Med. 1985 Jun 28;78(6B):32–37. doi: 10.1016/0002-9343(85)90361-4. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Kerttula Y., Leinonen M., Koskela M., Mäkelä P. H. The aetiology of pneumonia. Application of bacterial serology and basic laboratory methods. J Infect. 1987 Jan;14(1):21–30. doi: 10.1016/s0163-4453(87)90730-4. [DOI] [PubMed] [Google Scholar]
  16. Laussucq S., Schuster D., Alexander W. J., Thacker W. L., Wilkinson H. W., Spika J. S. False-positive DNA probe test for Legionella species associated with a cluster of respiratory illnesses. J Clin Microbiol. 1988 Aug;26(8):1442–1444. doi: 10.1128/jcm.26.8.1442-1444.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. McDade J. E., Shepard C. C., Fraser D. W., Tsai T. R., Redus M. A., Dowdle W. R. Legionnaires' disease: isolation of a bacterium and demonstration of its role in other respiratory disease. N Engl J Med. 1977 Dec 1;297(22):1197–1203. doi: 10.1056/NEJM197712012972202. [DOI] [PubMed] [Google Scholar]
  18. Rowbotham T. J. Current views on the relationships between amoebae, legionellae and man. Isr J Med Sci. 1986 Sep;22(9):678–689. [PubMed] [Google Scholar]
  19. Rowbotham T. J. Isolation of Legionella pneumophila from clinical specimens via amoebae, and the interaction of those and other isolates with amoebae. J Clin Pathol. 1983 Sep;36(9):978–986. doi: 10.1136/jcp.36.9.978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Rowbotham T. J. Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae. J Clin Pathol. 1980 Dec;33(12):1179–1183. doi: 10.1136/jcp.33.12.1179. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Smalley D. L., Jaquess P. A., Layne J. S. Selenium-enriched medium for Legionella pneumophila. J Clin Microbiol. 1980 Jul;12(1):32–34. doi: 10.1128/jcm.12.1.32-34.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Springer N., Ludwig W., Drozański W., Amann R., Schleifer K. H. The phylogenetic status of Sarcobium lyticum, an obligate intracellular bacterial parasite of small amoebae. FEMS Microbiol Lett. 1992 Sep 15;75(2-3):199–202. doi: 10.1016/0378-1097(92)90403-b. [DOI] [PubMed] [Google Scholar]
  23. Thacker W. L., Plikaytis B. B., Wilkinson H. W. Identification of 22 Legionella species and 33 serogroups with the slide agglutination test. J Clin Microbiol. 1985 May;21(5):779–782. doi: 10.1128/jcm.21.5.779-782.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Woese C. R. Bacterial evolution. Microbiol Rev. 1987 Jun;51(2):221–271. doi: 10.1128/mr.51.2.221-271.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]

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