Abstract
We investigated two fatal cases of invasive Haemophilus influenzae type b (Hib) infection in a community nursing home in western Sydney, Australia. Two elderly women had lived in the same room, and the onset of their illness was 5 days apart. Hib isolates from blood cultures showed identical profiles by pulsed field gel electrophoresis. These findings suggest that Hib infection was transmitted within this nursing home. Serious Hib disease may be underrecognized in this setting. Continued surveillance and serotyping of invasive H. influenzae disease is essential for identifying groups at increasing risk that may benefit from immunization against Hib.
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- Adams W. G., Deaver K. A., Cochi S. L., Plikaytis B. D., Zell E. R., Broome C. V., Wenger J. D. Decline of childhood Haemophilus influenzae type b (Hib) disease in the Hib vaccine era. JAMA. 1993 Jan 13;269(2):221–226. [PubMed] [Google Scholar]
- Alho O. P., Jokinen K., Pirilä T., Ilo A., Oja H. Acute epiglottitis and infant conjugate Haemophilus influenzae type b vaccination in northern Finland. Arch Otolaryngol Head Neck Surg. 1995 Aug;121(8):898–902. doi: 10.1001/archotol.1995.01890080066013. [DOI] [PubMed] [Google Scholar]
- Barbour M. L., Mayon-White R. T., Coles C., Crook D. W., Moxon E. R. The impact of conjugate vaccine on carriage of Haemophilus influenzae type b. J Infect Dis. 1995 Jan;171(1):93–98. doi: 10.1093/infdis/171.1.93. [DOI] [PubMed] [Google Scholar]
- Berg S., Trollfors B., Nylén O., Hugosson S., Prellner K., Carenfelt C. Incidence, aetiology, and prognosis of acute epiglottitis in children and adults in Sweden. Scand J Infect Dis. 1996;28(3):261–264. doi: 10.3109/00365549609027168. [DOI] [PubMed] [Google Scholar]
- Casadevall A., Dobroszycki J., Small C., Pirofski L. A. Haemophilus influenzae type b bacteremia in adults with AIDS and at risk for AIDS. Am J Med. 1992 Jun;92(6):587–590. doi: 10.1016/0002-9343(92)90774-6. [DOI] [PubMed] [Google Scholar]
- Farley M. M., Stephens D. S., Brachman P. S., Jr, Harvey R. C., Smith J. D., Wenger J. D. Invasive Haemophilus influenzae disease in adults. A prospective, population-based surveillance. CDC Meningitis Surveillance Group. Ann Intern Med. 1992 May 15;116(10):806–812. doi: 10.7326/0003-4819-116-10-806. [DOI] [PubMed] [Google Scholar]
- Frantz T. D., Rasgon B. M. Acute epiglottitis: changing epidemiologic patterns. Otolaryngol Head Neck Surg. 1993 Sep;109(3 Pt 1):457–460. doi: 10.1177/019459989310900311. [DOI] [PubMed] [Google Scholar]
- Howard A. J., Owens D., Musser J. M. Cross-infection due to Haemophilus influenzae type b in adults. J Hosp Infect. 1991 Sep;19(1):70–72. doi: 10.1016/0195-6701(91)90131-q. [DOI] [PubMed] [Google Scholar]
- Mayo-Smith M. F., Spinale J. W., Donskey C. J., Yukawa M., Li R. H., Schiffman F. J. Acute epiglottitis. An 18-year experience in Rhode Island. Chest. 1995 Dec;108(6):1640–1647. doi: 10.1378/chest.108.6.1640. [DOI] [PubMed] [Google Scholar]
- Patterson J. E., Madden G. M., Krisiunas E. P., Masecar B., Hierholzer W. J., Jr, Zervos M. J., Lyons R. W. A nosocomial outbreak of ampicillin-resistant Haemophilus influenzae type b in a geriatric unit. J Infect Dis. 1988 May;157(5):1002–1007. doi: 10.1093/infdis/157.5.1002. [DOI] [PubMed] [Google Scholar]
- Peltola H., Kilpi T., Anttila M. Rapid disappearance of Haemophilus influenzae type b meningitis after routine childhood immunisation with conjugate vaccines. Lancet. 1992 Sep 5;340(8819):592–594. doi: 10.1016/0140-6736(92)92117-x. [DOI] [PubMed] [Google Scholar]
- Smith P. F., Stricof R. L., Shayegani M., Morse D. L. Cluster of Haemophilus influenzae type b infections in adults. JAMA. 1988 Sep 9;260(10):1446–1449. [PubMed] [Google Scholar]