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. 1998 Jan-Mar;4(1):105–111. doi: 10.3201/eid0401.980115

Bayou virus-associated hantavirus pulmonary syndrome in Eastern Texas: identification of the rice rat, Oryzomys palustris, as reservoir host.

N Torrez-Martinez 1, M Bharadwaj 1, D Goade 1, J Delury 1, P Moran 1, B Hicks 1, B Nix 1, J L Davis 1, B Hjelle 1
PMCID: PMC2627679  PMID: 9452404

Abstract

We describe the third known case of hantavirus pulmonary syndrome (HPS) due to Bayou virus, from Jefferson County, Texas. By using molecular epidemiologic methods, we show that rice rats (Oryzomys palustris) are frequently infected with Bayou virus and that viral RNA sequences from HPS patients are similar to those from nearby rice rats. Bayou virus is associated with O. palustris; this rodent appears to be its predominant reservoir host.

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Selected References

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  1. Duchin J. S., Koster F. T., Peters C. J., Simpson G. L., Tempest B., Zaki S. R., Ksiazek T. G., Rollin P. E., Nichol S., Umland E. T. Hantavirus pulmonary syndrome: a clinical description of 17 patients with a newly recognized disease. The Hantavirus Study Group. N Engl J Med. 1994 Apr 7;330(14):949–955. doi: 10.1056/NEJM199404073301401. [DOI] [PubMed] [Google Scholar]
  2. Hjelle B., Goade D., Torrez-Martinez N., Lang-Williams M., Kim J., Harris R. L., Rawlings J. A. Hantavirus pulmonary syndrome, renal insufficiency, and myositis associated with infection by Bayou hantavirus. Clin Infect Dis. 1996 Sep;23(3):495–500. doi: 10.1093/clinids/23.3.495. [DOI] [PubMed] [Google Scholar]
  3. Hjelle B., Jenison S., Torrez-Martinez N., Herring B., Quan S., Polito A., Pichuantes S., Yamada T., Morris C., Elgh F. Rapid and specific detection of Sin Nombre virus antibodies in patients with hantavirus pulmonary syndrome by a strip immunoblot assay suitable for field diagnosis. J Clin Microbiol. 1997 Mar;35(3):600–608. doi: 10.1128/jcm.35.3.600-608.1997. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Hjelle B., Tórrez-Martínez N., Koster F. T., Jay M., Ascher M. S., Brown T., Reynolds P., Ettestad P., Voorhees R. E., Sarisky J. Epidemiologic linkage of rodent and human hantavirus genomic sequences in case investigations of hantavirus pulmonary syndrome. J Infect Dis. 1996 Apr;173(4):781–786. doi: 10.1093/infdis/173.4.781. [DOI] [PubMed] [Google Scholar]
  5. Jenison S., Yamada T., Morris C., Anderson B., Torrez-Martinez N., Keller N., Hjelle B. Characterization of human antibody responses to four corners hantavirus infections among patients with hantavirus pulmonary syndrome. J Virol. 1994 May;68(5):3000–3006. doi: 10.1128/jvi.68.5.3000-3006.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Khan A. S., Gaviria M., Rollin P. E., Hlady W. G., Ksiazek T. G., Armstrong L. R., Greenman R., Ravkov E., Kolber M., Anapol H. Hantavirus pulmonary syndrome in Florida: association with the newly identified Black Creek Canal virus. Am J Med. 1996 Jan;100(1):46–48. doi: 10.1016/s0002-9343(96)90010-8. [DOI] [PubMed] [Google Scholar]
  7. Khan A. S., Spiropoulou C. F., Morzunov S., Zaki S. R., Kohn M. A., Nawas S. R., McFarland L., Nichol S. T. Fatal illness associated with a new hantavirus in Louisiana. J Med Virol. 1995 Jul;46(3):281–286. doi: 10.1002/jmv.1890460320. [DOI] [PubMed] [Google Scholar]
  8. Ksiazek T. G., Peters C. J., Rollin P. E., Zaki S., Nichol S., Spiropoulou C., Morzunov S., Feldmann H., Sanchez A., Khan A. S. Identification of a new North American hantavirus that causes acute pulmonary insufficiency. Am J Trop Med Hyg. 1995 Feb;52(2):117–123. doi: 10.4269/ajtmh.1995.52.117. [DOI] [PubMed] [Google Scholar]
  9. Morzunov S. P., Feldmann H., Spiropoulou C. F., Semenova V. A., Rollin P. E., Ksiazek T. G., Peters C. J., Nichol S. T. A newly recognized virus associated with a fatal case of hantavirus pulmonary syndrome in Louisiana. J Virol. 1995 Mar;69(3):1980–1983. doi: 10.1128/jvi.69.3.1980-1983.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Nolte K. B., Feddersen R. M., Foucar K., Zaki S. R., Koster F. T., Madar D., Merlin T. L., McFeeley P. J., Umland E. T., Zumwalt R. E. Hantavirus pulmonary syndrome in the United States: a pathological description of a disease caused by a new agent. Hum Pathol. 1995 Jan;26(1):110–120. doi: 10.1016/0046-8177(95)90123-x. [DOI] [PubMed] [Google Scholar]
  11. Rawlings J. A., Torrez-Martinez N., Neill S. U., Moore G. M., Hicks B. N., Pichuantes S., Nguyen A., Bharadwaj M., Hjelle B. Cocirculation of multiple hantaviruses in Texas, with characterization of the small (S) genome of a previously undescribed virus of cotton rats (Sigmodon hispidus). Am J Trop Med Hyg. 1996 Dec;55(6):672–679. doi: 10.4269/ajtmh.1996.55.672. [DOI] [PubMed] [Google Scholar]
  12. Rollin P. E., Ksiazek T. G., Elliott L. H., Ravkov E. V., Martin M. L., Morzunov S., Livingstone W., Monroe M., Glass G., Ruo S. Isolation of black creek canal virus, a new hantavirus from Sigmodon hispidus in Florida. J Med Virol. 1995 May;46(1):35–39. doi: 10.1002/jmv.1890460108. [DOI] [PubMed] [Google Scholar]
  13. Schmaljohn C., Hjelle B. Hantaviruses: a global disease problem. Emerg Infect Dis. 1997 Apr-Jun;3(2):95–104. doi: 10.3201/eid0302.970202. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Song J. W., Baek L. J., Gajdusek D. C., Yanagihara R., Gavrilovskaya I., Luft B. J., Mackow E. R., Hjelle B. Isolation of pathogenic hantavirus from white-footed mouse (Peromyscus leucopus) Lancet. 1994 Dec 10;344(8937):1637–1637. doi: 10.1016/s0140-6736(94)90430-8. [DOI] [PubMed] [Google Scholar]
  15. Torrez-Martinez N., Hjelle B. Enzootic of Bayou hantavirus in rice rats (Oryzomys palustris) in 1983. Lancet. 1995 Sep 16;346(8977):780–781. doi: 10.1016/s0140-6736(95)91541-9. [DOI] [PubMed] [Google Scholar]

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