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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1994 Jan;32(1):205–208. doi: 10.1128/jcm.32.1.205-208.1994

VP4 genotyping of human rotavirus in the United States.

N Santos 1, M Riepenhoff-Talty 1, H F Clark 1, P Offit 1, V Gouvea 1
PMCID: PMC262997  PMID: 8126181

Abstract

The VP4 (P) and VP7 (G) types of 171 rotavirus isolates obtained from children with diarrhea in the United States were characterized by PCR typing assays. Strains P1G1 predominated (71%); this was followed by strains P1G3 (20%) and P2G2 and P1G4 (2% each). Mixed types were identified in five (3%) specimens. Two (1%) strains bearing the P3 genotype (P3G1 and P3G2) were found in children with severe dehydrating diarrhea, although the P3 genotype has been regarded as a possible marker for virus attenuation.

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Selected References

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