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. Author manuscript; available in PMC: 2009 Dec 9.
Published in final edited form as: Vaccine. 2008 Oct 16;26(52):6874–6882. doi: 10.1016/j.vaccine.2008.09.077

Figure 6. Mice given levofloxacin at 72 hours post-infection are immune to subsequent challenge with SCHU S4.

Figure 6

Mice were infected via intra-nasal challenge (88 CFU) and treated with levofloxacin at varying times post-infection (Post) as described in Figure 2. At 72, 96, and 120 hours post-infection, mice were divided into groups (ten mice per group) and given levofloxacin 40 mg/kg/body weight. Mice were then housed for 55 days, and then challenged intra-nasally with approximately 3 LD50 doses (116 CFU) of Schu 4. Mice (10 per group) were monitored twice daily for up to one month.